Chronic rhinosinusitis restricts the quality of life of millions of involved patients. The aim of the study was to evaluate how functional endoscopic sinus surgery (FESS) modifies symptom profiles in patients with chronic rhinosinusitis. Questionnaires were given to eighty patients with chronic rhinosinusitis, who underwent FESS, to assess typically related symptoms preoperatively and postopera...

OBJECTIVES To evaluate nasal mucus glucose concentrations in patients with and without chronic rhinosinusitis and determine if corticosteroid therapy alters mucus glucose. STUDY DESIGN Prospective observational study. SETTING Single tertiary care center. SUBJECTS Ninety-five patients presenting to an otolaryngology clinic. METHODS Participants completed questionnaires that included a hi...

METFORMIN: OPTIMAL DOSING AND MYTHS SURROUNDING LACTIC ACIDOSIS ccording to the CDC, acute upper respiratory infections are the 3rd leading primary diagnosis at ambulatory care office visits in the U.S.1 One of the more common upper respiratory infections is rhinosinusitis which describes an inflammation of one or more of the paranasal sinuses.2 Symptoms, which last 4 weeks or fewer in acute ca...

There is evidence that a link exists between the upper and lower respiratory tracts. During the last fifty years many clinical observations has lead to a new pathogenic view of rhinosinusitis and asthma defined as Sinobronchial Syndrome. The inflammatory process in the nose and bronchi explains some of the complex interactions among different clinical diseases, such as rhinosinusitis, asthma, b...

We sought to explore the therapeutic potential of xylitol irrigations in treating chronic rhinosinusitis (CRS). Saline irrigation, which has been shown to be beneficial for patients with rhinosinusitis, served as an accepted standard treatment for comparison. We conducted a prospective, randomized, crossover study to compare the therapeutic value of saline versus xylitol irrigations in patients...

BACKGROUND/AIMS To determine if patients with benign paroxysmal positional vertigo (BPPV) have a higher frequency of rhinosinusitis than people with normal vestibular function. METHODS The subjects were 52 patients with BPPV and 46 normal people. Every subject had a sinus CT scan, a blood draw for IgE and a rhinologic examination by an otolaryngologist. RESULTS The frequency of rhinosinusit...

OBJECTIVE To generalize the prescribing trends of a statistically defined sample of patient visits because of acute or chronic rhinosinusitis in the United States, using reported diagnostic codes from the International Classification of Diseases, Ninth Revision, Clinical Modification. DESIGN Four-year prospective study. SETTING Public use data from the National Ambulatory Medical Care Surve...

INTRODUCTION Symptomatology, nasal endoscopy and Computerised Tomographic (CT) scan have been used to diagnose chronic rhinosinusitis. The value of disease severity score in the assessment of chronic rhinosinusitis has not been well investigated. Hence, this study aims to correlate the pre-operative symptom severity score as well as overall disease severity score of patients with chronic rhinos...

A growing amount of scientific evidence suggests that herbal medicine may be helpful as an adjuvant treatment in rhinosinusitis. Herein, we systematically review and determine the role, efficacy and safety of phytotherapy in the treatment of acute and chronic rhinosinusitis and establish the qualities of herbal drugs as demonstrated by in vitro and in vivo experiments. Eligible studies publishe...

BACKGROUND A core outcome set (COS) is an agreed standardised collection of outcomes that should be measured and reported by all trials for a specific clinical area, in this case chronic rhinosinusitis. These are not restrictive and researchers may continue to explore other outcomes alongside these that they feel are relevant to their intervention. The aim of this systematic review was to ident...