rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. it is characterized by chronic joint inflammation and variable degrees of bone and cartilage erosion. oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis. reactive oxygen species (ros) are produc...

background: rheumatoid arthritis (ra) is a chronic inflammatory disease with many genetic factors predisposing to disease susceptibility. the aim of the present study was to investigate the impact of cd226 rs727088 and rs763361 polymorphisms and susceptibility to ra in a sample of the iranian population. methods: this case-control study was carried out on 100 patients with ra and 104 healthy su...

purpose : the main ocular manifestation of rheumatoid arthritis is dry eye. lacritin is a secreted glycoprotein of tear and when applied topically in rabbits, it increased the volume of basal tear secretion. so the aim of this study was to compare lacritin level in rheumatoid arthritis (ra) and control group. methods : this cross-sectional study was done on 40 patients with ra and 48 healthy su...

septic arthritis of the hip in children has multiple sequelae and may result in severe disability. significant morbidity can be prevented by early recognition and treatment. the authors reviewed 13 children with 14 hips with sequelae of septic arthritis of the hip. all of children had history of hip septic arthritis before age of 4 years. six were male subjects, and 7 were female subjects. we e...

objective (s):rheumatoid arthritis (ra) is a chronic systemic inflammatory disorder, primarily targeting the synovium and articular cartilage that leads to joint damage. recent reports have suggested the role of adipocytokines in mediating joint damage; however it still is a matter of debate. the purpose of this study was to evaluate the association between serum values of adiopocytokines (lept...

d-penicillamine is one of the disease-modifying anti-rheumatic drugs (dmards). drug-induced pemphigus is not frequently associated with d-penicillamine, and to date, the number of reported cases is about a hundred. most reports of d-penicillamine-induced pemphigus vulgaris are in patients with rheumatoid arthritis. it has rarely been reported in patients not taking d-penicillamine. we report a ...