Background The results showed that there was a certain correlation between the single nucleotide polymorphism of IL-10-1082G/A and rheumatic heart disease, but there was no systematic study to verify this conclusion. Aims Systematic review of the association between single nucleotide polymorphism of IL-10-1082G/A locus and rheumatic heart disease. Materials and Methods Computer retrieval Pu...

Rheumatic heart disease is still a relevant problem in children, adolescents and young adults. Molecular mimicry between streptococcal and human proteins has been proposed as the triggering factor leading to autoimmunity and tissue damage in rheumatic heart disease. Despite the widespread application of Jones' criteria, carditis is either underdiagnosed or overdiagnosed. Endocarditis leading to...

Rheumatic fever is an inflammatory disease that may develop after an infection with group A 1, 2 Streptococcus bacteria. The disease can affect the heart, joints, skin and brain. Complications of rheumatic fever are arrhythmias, damage to the heart valves, endocarditis, heart failure, pericarditis and 3 Sydenham's chorea. The most important way to prevent rheumatic fever is by getting quick tre...

BACKGROUND Although low socioeconomic status, and environmental factors are known risk factors for rheumatic heart disease in other societies, risk factors for rheumatic heart disease remain less well described in Uganda. AIMS AND OBJECTIVE The objective of this study was to investigate the role of socio-economic and environmental factors in the pathogenesis of rheumatic heart disease in Ugan...

BACKGROUND As the pathogenesis of Sneddon's syndrome is unknown, research for associated disease can facilitate our understanding. CASE DESCRIPTION Of nine patients with Sneddon's syndrome, three had rheumatic heart disease (mitral valve stenosis, regurgitation, or both) due to rheumatic fever or Sydenham's chorea. Transient anticardiolipin antibodies or positive skin lupus band test were pre...

enterococci are normal inhabitants of gastrointestinal tract, being responsible for 5 to 18% of infective endocarditis and the incidence appears to be increasing. eleven patients with enterococcal endocarditis were studied. in a case series group, 10 men (average 57 years) and one woman (37 years) were studied. two patients had rheumatic heart disease, 5 patients arteriosclerotic disease and on...