Introduction/Aim: Haemolytic disease of the newborn is haemolytic anaemia that occurs as a consequence mismatched blood parents, is, mismatch elements between mother and fetus in ABO or Rh system. The aim this study to report case which occurred result incompatibility. Case report: Indirect hyperbilirubinemia was registered female 18th hour life. group A (D) positive, direct Coombs test positiv...

BACKGROUND Hyperbilirubinemia is a common disorder during the neonatal period. Severe neonatal hyperbilirubinemia (NH) carries a potential for permanent neurological impairment. The current study analyzed possible etiologies leading to NH. METHODS A retrospective cohort of neonates with total serum bilirubin (TSB) ≥ 20 mg/dL was surveyed from 1995 to 2007. Subjects with gestational ages < 34 ...

BACKGROUND Bone marrow transplantation with minor ABO incompatibility may be followed by moderate delayed hemolysis of the recipient's red cells by donor-derived ABO antibodies. This reaction may be more severe after transplantation of peripheral blood progenitor cells (PBPCs). CASE REPORT A 16-year-old boy underwent an allogeneic PBPC transplant from his HLA-mismatched mother as treatment fo...

INTRODUCTION With the increased utilization of immunohematology (IH) analyzers in the transfusion medicine, type, and screen policy is the method of choice. Still, the importance of routine crossmatching could not be overruled. Here, we tried to understand the clinical conditions and safety of red cell transfusion and their outcomes. MATERIALS AND METHODS This prospective study was conducted ...

In rhesus-negative women who have had previous babies severely affected by rhesus incompatibility, the maternal rhesus antibody titre during a subsequent pregnancy offers only a poor indication of the degree to which the developing foetus will be affected. This has induced workers to look for laboratory tests that can give more reliable information. In an attempt to detect excessive haemolysis ...

The red cells of 63 members of 11 families were tested with (125)I-labeled anti-Rh(0)(D). Families with a history of hemolytic disease of the newborn due to fetomaternal Rh incompatibility were selected for study. In such families it was possible to determine the antibody binding to the Rh(0)(D) heterozygous red cells of the children and to compare within each family this value with the antibod...

Background: Immune-mediated haemolytic disease of the newborn refers to a specific category anaemia that results from transplacental passage IgG antibodies pre-sensitized mother her fetus in utero. This occurs due blood group incompatibility between and fetus. The clinical presentation covers wide spectrum spanning still births erythroblastosis fetalis as well infants born with only mild haemol...

In most insects, the endosymbiont Wolbachia induces cytoplasmic incompatibility (CI), an embryonic mortality observed when infected males mate either with uninfected females or with females infected by an incompatible Wolbachia strain. Although the molecular mechanism of CI remains elusive, it is classically viewed as a modification-rescue model, in which a Wolbachia mod function disables the r...