Synchrotron X-ray diffraction coupled to atomic pair distribution function analysis and Reverse Monte Carlo simulations is used to determine the atomic-scale structure of Ru nanoparticle catalysts for the Fischer-Tropsch reaction. The rate of CO hydrogenation strongly correlates with the abundance of surface atoms with coordination numbers of 10 and 11. DFT calculations confirm that CO dissocia...

Two solvated cobalt(ii) terpyridine complexes, [Co(MeO-terpy)2](BF4)2·H2O (·H2O) and [Co(MeO-terpy)2](BF4)2·acetone (·acetone) were prepared. Annealing each of these complexes resulted in the formation of two desolvated species, and , respectively. ·H2O and exhibited two-step and gradual SCO. The compound ·acetone has high-spin at all temperatures and undergoes a reverse spin transition due to ...

Background Assays that are used for the diagnosis and management of HIV-1 infection are subject to assay interference(s) and co-infection with HCV may interfere with HIV-1 genotyping and/or phenotyping. Since a third of HIV-1 infected patients are frequently HCV co-infected, there is an increasing need to assess the effect of HCV coinfection on the accuracy of the HIV-1 protease (PR) and revers...

We examine using a CASE tool, Interactive Development Environ-ment's Software through Pictures (StP), to support reverse engineering. We generate structure charts in StP from the automated analysis of C source code. The advantages of this approach are that one can use the CASE tool's support for drawing, linking, and modifying pictorial notations for program design in order to make it easier to...

Policy distortions are provoking unnecessarily early retirement Average effective retirement ages have declined in many OECD countries over the past three decades, and cross-country differences have become wide (Figure 1). Reversing this past decline would raise the labour force participation and employment of older workers. This in turn would ease the adjustment to ageing populations, curb age...

Reverse engineering problems for conjunctive queries (CQs), such as query by example (QBE) or definability, take a set of user examples and convert them into an explanatory CQ. Despite their importance, the complexity of these problems is prohibitively high (coNEXPTIME-complete). We isolate their two main sources of complexity and propose relaxations of them that reduce the complexity while hav...

OBJECTIVES Human immunodeficiency virus (HIV)-infected patients are frequently co-infected with hepatitis B and/or C virus (HBV/HCV). The safety of etravirine was investigated over 96 weeks in patients co-infected with HIV type-1 (HIV-1) and HBV and/or HCV in the Phase III DUET trials. DUET-1 and DUET-2 are registered with clinicaltrials.gov (NCT00254046 and NCT00255099, respectively). METHOD...

Small RNA pseudoknots, selected to bind human immunodeficiency virus type 1 (HIV-1) reverse transcriptase tightly, are potent inhibitors of reverse transcriptase. The co-crystal structure of reverse transcriptase complexed with a 33 nucleotide RNA pseudoknot has been determined by fitting the ligand into a high quality, 4-fold averaged 4.8 A resolution electron density map. The RNA is kinked be...