This review summarizes the knowledge and highlights recent advances in clinical research of retinopathy of prematurity (ROP). This disease is still important, because improvements in neonatal intensive care during the last years have increased the survival of the most immature newborns, but did not diminish the ROP frequency. Ophthalmologic screening and, if applicable, laser treatment at the o...

When the condition of retrolental fibroplasia was first described by Terry (1942) in the United States of America it was then only recognized in the advanced state of a cicatricial mass or membrane behind the lens. It is now appreciated, however, that the earliest pathological changes occur in the nerve fibre layer of the retina, which first of all becomes thickened as a result of oedema, trans...

Intruduction: This study was conducted to determine blood levels of leptin in premature infants with proliferative ROP.Retinopathy of prematurity (ROP) is a postnatal disorder of retinal vessels that develops in the incompletely vascularized retina of preterm infants. This disorder regresses in most patients but can lead to severe visual impairment. There is evidence that leptin stimulates angi...

Retinopathy of prematurity (ROP) is a disorder characterised by abnormal retinal vascular development, and several risk factors are involved. The condition may be in mild form or it may result in retinal detachment which may eventually cause blindness. The management of the risk factors involved in the disease etiopathogenesis and the treatment by laser photocoagulation performed in early stage...

Background: Retinopathy of prematurity (ROP) is a common cause of blindness and accounts for up to 10% of childhood blindness in developed countries. Also Before surfactant became available in the NICU, an incidence of 11% to 60% was reported in the VLBW population. However, there are few studies on the incidence of ROP among low-birth-weight (LBW) infants in Iran and the aim of this study is d...