AIM/BACKGROUND A new defect in the anticoagulant system has recently been discovered--activated protein C resistance. The frequency of this disorder has been shown to be increased in young patients (< 50 years of age) with central retinal vein occlusion. This study was carried out to determine if there was any overrepresentation of activated protein C resistance in patients > 50 years of age wi...

Retinal vein occlusion is one of the most common causes of retinal vascular abnormality and a frequent cause of vision loss. It is an obstruction of the retinal venous system by thrombus formation and may involve the central, hemicentral or branch retinal vein. It typically occurs in middle-aged and elderly patients, and its increased occurrence is therefore associated with the increased aging ...

Uncontrolled hypertension is well- known to give rise to systemic complications involving multiple central organs. Artherosclerosis leads to damage of the retinal vessels wall, contributing to venous stasis, thrombosis and finally, occlusion. Retinal vein occlusions compromise vision through development of ischaemic maculopathy, macular oedema, and rubeotic glaucoma. Laser photocoagulation rema...

Neovascularization after retinal branch vein occlusion (RBVO) has long been recognized (Foster Moore, 1924; Jensen, 1936) and it has been noted more recently in a number of publications. Krill, Archer, and Newell (I97I) found that three out of 14 patients had new vessel formation after RBVO; Michels and Gass (1974) found seven cases of retinal new vessels in 28 eyes and disc new vessels in two ...

C entral retinal vein occlusion (CRVO) in the young is also known as papillophlebitis and is a rare presentation.1 Retinal vein occlusion has been known to be associated with many systemic conditions.1,2 Association of hyperhomocysteinemia with retinal vein occlusion was reported in the literature.2-4 There was controversy, however, over whether there was correlation between methylenetetrahydro...