Comprised mainly of monocytes and tissue macrophages, the reticuloendothelial system (RES) plays two major roles in iron metabolism: it recycles iron from senescent red blood cells and it serves as a large storage depot for excess iron. Although iron recycling by the RES represents the largest pathway of iron efflux in the body, the precise mechanisms involved have remained elusive. However, st...

Introduction The role of fatty acids in the reticuloendothelial system has been studied in a variety of ways, including dietary modification of tissue [ 1-41, analysis of the effects of exogenous fatty acids in vitro [S-91 and investigation of the enzymes of fatty acid metabolism [ 10191. These approaches have indicated a unique and selective role for arachidonic acid in cell signalling in the ...

Wistar strain albino rats of either sex were subjected to acute noise stress (3000 Hz at > 97 dB) for 30 minutes. Carbon clearance test was conducted in noise stressed animals immediately after the stress period. Significant (P < 0.001) increase of the clearance constant K was observed in stressed animals compared to the controls, indicating increased phagocytic activity of the reticuloendothel...

This study was undertaken to investigate the in vivo phagocytic activity and clearancerates of Telfairia occidentalis plant additive using carbon clearance assay. Wistaralbino rats were used this study. The injected with ink through thetail vein while blood samples collected at intervals though orbital usingcapillary tubes. results showed that T. occidentals leaves had ability tosignificantly (...

A circadian rhythm was demonstrated in 10 males and 10 females with respective mean decreases in plasma iron concentration at 18 hr of 62% and 47% of morning values. Ferrokinetic studies performed on 5 normal males and 5 normal females showed a more rapid disappearance rate and lower plasma iron turnover in the evening. Parallel studies were done on 6 normal males in the morning and 4 normal ma...

Granulomatous lesions affecting the reticuloendothelial system produce a group of disorders having certain striking clinical features. The condition known as Hand-Schuller-Christian disease is one of this group, and the well-known SchiillerChristian triad of exophthalmos, diabetes insipidus, and multiple lesions in the skull was for many years considered to be pathognomonic. More recently Otani...

• Arterial lesions resembling arteriosclerosis produced by reticuloendothelial system blockade have been demonstrated by Patek and Bernickwho injected carbon or thorium dioxide into rats and rabbits; by Shimamoto who injected tissue and bacterial potysaecharides, bacterial exotoxins, killed bacteria, dextran and glycogen, and kaolin into rabbits, rats and guinea pigs; by Lautsch et al. who inje...

Part A is concerned with more basic aspects of reticuloendothelial function ranging from lymphocyte kinetics to biochemical events in reticuloendothelial cells. A section entitled "The Phagocytic Event" is particularly concise and cogent. My major disappointment in this volume is with the photographs. For example, Meuret's elegant study on the geography of short and long-lived lymphocytes loses...

1. For the purpose to clarify the role of reticuloendothelial cells in the center of erythroblastic islet, the medullary and extramedullary erythropoietic foci in convalescence of phenylhydrazine arternia were observed by light and electron microscopies, and the mode of development of anemia in rabbit having blocked RES. 2. Light microscopic observations revealed the stimulated formation of ery...

The phenomenon has dassically been produced in the rabbit by bacterial endotoxins (2) and results from the widespread occlusion of glomerular capillaries by dense fibrin deposits (3-5). Two basic conditions (3) appear essential for the development of the lesion: (a) the slow activation of intravascular coagulation with the formation of fibrin aggregates in the circulating blood, and (b) the inh...