Abstract According to selective, retentive, scientific realism, past empirical success may be explained only by the parts of theories that are responsible their successful predictions being approximately true, and thus theoretically retained, or approximated, posterior same predictions. In this article, we present as case study transit from Ptolemy’s Kepler’s astronomy, for Mars’ orbit. We an a...

The floating microsphere's purpose is to improve gastric retention time. Floating drug delivery systems are lower in bulk thickness than juice and remain on for a long period of time without impacting the gastric-emptying rate increasing bioavailability. Gastro-retentive microspheres particularly suitable continuous or late release oral formulations with blending versatility achieve various pat...

this study is focused on investigating the parameters of laser percussion drilling process of nickel-base super alloy inconel 718 with thickness of 1 mm. fiber laser with the power of 500 watts was used as the laser source. laser pulse frequency, duty cycle, laser power, focal point position, were assumed as the laser drilling process variables. the hole geometry features, i.e. entrance hole di...

Oral appliance (OA) therapy with a mandibular advancement device (OAm) is a non-invasive, alternative approach to maintaining upper airway patency. The main requirement for an OAm to be effective is the adequate retention on the teeth while the patient is asleep. We evaluated the retentive forces of a new low-cost, customizable, titratable, thermoplastic OAm (BluePro (®); BlueSom, France). Dent...

Intragastric buoyant tablets, i.e., gastro retentive drug delivery systems of Amoxycillin trihydrate were prepared with the objective to obtain site-specific drug delivery for the stomach and to extend its duration of action. The sustained release of amoxicillin is desired because of its short biological half-life. Part icularly to treat Helicobacter pylori infections, the sustained release is ...

In the present research, the mixed-mode fracture mechanics analysis in a plate with central hole under tensile loading is considered. It is assumed that a plate containing two symmetrical hole-edge cracks is bonded with two dissimilar planes. The stress intensity factors at the crack tips are calculated. The problem is modeled in Casca software and this model is analyzed with Franc software. Th...