the effects of adenosine,5-n-ethylcarbox-amidoadenosine (neca), 2-chloroadenosine (2-ca), n6-phenyiisopropyladenos'tne (l-pia and d-pia) and n6 -cyclohexyladenos'tne (cha) were examined on the mouse isolated vas deferens. all the compounds in a concentration-dependent manner inhibited electrically induced contrac¬tions. ic of adenosine and its analogues were 13.68 ± 5.97 for ado, 0.736 ± 0.087 ...

Temperature shift is often practiced in the cultivation of Escherichia coli to reduce undesired metabolite formation and to maximize synthesis of correctly folded heterologous protein. As the culture temperature is decreased below the optimal 37 degrees C, growth rate decreases and many physiological changes occur. In this study, we investigated the gene expression dynamics of E. coli on switch...

Previous research in the domain of social comparison theory has suggested that the same factors that have been hypothesized as antecedents to response shift, primarily significant life events, also prompt an increase in interest in social comparison. Based on this research, it is suggested that social comparison, or more specifically, change in social comparison, is a mediator of the relation b...

BACKGROUND AND AIMS The etiology and pathophysiology of stomach carcinoma is complex, and the mechanism whereby H. pylori directly or indirectly induces carcinoma remains unclear. In this study, interleukin (IL)-8, IL-4 and interferon (IFN)-gamma were measured in the tissue culture supernatant of gastric organ cultures from subjects with chronic gastritis with or without H. pylori infection, an...

The technique that we use for pattern shift visual evoked response (PSVER) is described. PSVER is a non-invasive, practical and reliable clinical test in detecting anterior visual pathways lesions even when asymptomatic. The ability to find unsuspected lesions in multiple sclerosis, making possible an early diagnosis, is underscored. We also discuss some pathophysiologic aspects and the finding...

Jetlag results when a temporary loss of circadian entrainment alters phase relationships among internal rhythms and between an organism and the outside world. After a large shift in the light-dark (LD) cycle, rapid recovery of entrainment minimizes the negative effects of internal circadian disorganization. There is evidence in the existing literature for an activation of the hypothalamic-pitui...

BACKGROUND The purpose of this study was to investigate the scale recalibration construct of response shift and its relationship to glycemic control in children with diabetes. METHODS At year 1, thirty-eight children with type 1 diabetes attending a diabetes summer camp participated. At baseline and post-camp they completed the Problem Areas in Diabetes (PAID) questionnaire. Post-camp, the PA...