OBJECTIVE To evaluate the diagnostic accuracy of the rapid influenza antigen detection test (RIADT) and determine which symptoms are relevant to results. DESIGN Single-centre, cross-sectional study. SETTING Primary care centre, Tokyo, Japan. PARTICIPANTS 82 consecutive outpatients presenting with upper respiratory symptoms and fever ≥37°C at any time from symptom onset, between December 2...

1. Evidence is presented indicating the presence of a filtrable virus in the nasopharyngeal secretions of individuals suffering from influenza. 2. An attempt to transfer influenza from one human being to another by means of filtered nasopharyngeal washings resulted in the production in the inoculated volunteer of a common cold. 3. A filtrable agent has been cultivated in tissue medium from the ...

BACKGROUND Guaifenesin is a component of medicines used to improve symptoms associated with upper respiratory tract infections. Patient-reported outcome instruments are valuable for evaluating symptom improvements; however, a validated tool to assess efficacy of mucoactive drugs does not exist. We compared the efficacy of extended-release guaifenesin with placebo for treatment of symptoms of up...

OBJECTIVE To evaluate the prevalence of respiratory symptoms as the motive for emergency room visits by adult and pediatric patients, describing the major clinical syndromes diagnosed and the outcomes of the patients. METHODS A cross-sectional study conducted in the emergency room of a tertiary care university hospital. Between November of 2008 and November of 2009, we reviewed the total numb...

BACKGROUND Air pollution is known to be a leading cause of respiratory symptoms. Many cross-sectional studies reported that air pollution caused respiratory disease in Japanese individuals in the 1960s. Japan has laws regulating air pollution levels and providing compensation for victims of pollution-related respiratory disease. However, long-term changes in respiratory function and symptoms in...

BACKGROUND The current prospective study investigated the hypothesis of metal fume fever (MFF) being a predictor for the development of respiratory symptoms and functional abnormalities. METHODS The study consisted of a pre-exposure and two follow up assessments of 286 welding apprentices during an average period of 15 months. A respiratory and a systemic symptom questionnaire, skin prick tes...

OBJECTIVE To evaluate the respiratory rate as an indicator of hypoxia in infants < 2 months of age. SETTING Pediatric emergency unit of an urban teaching hospital. SUBJECTS 200 infants < 2 months, with symptom(s) of any acute illness. METHODS Respiratory rate (by observation method), and oxygen saturation (SaO(2)) by means of a pulse oximeter were recorded at admission. Infants were categ...

BACKGROUND Infants with chronic respiratory symptoms should be evaluated thoroughly because there are various causes which are different from those of children and adolescents. OBJECTIVE This study was designed to investigate the relationship between chronic respiratory symptoms and bedtime bottle feeding in infants after the age of 6 months. METHODS We conducted a prospective study that in...

The aim of this study was to investigate the rate of transmission of respiratory viral infections to children visiting the emergency room of a large pediatric hospital during winter. A total of 615 children were prospectively studied. Twenty-two (3·6%) children developed at least one symptom compatible with a respiratory viral infection within 1-7 days after the visit, including cough (12 child...