Background: Late preterm neonates may have the external appearance and behavior similar to their counterparts.However, they are susceptible to various neonatal morbidities , due to their physiological and metabolical immaturity.To assess the correlation between cord blood arterial lactate levels and base excess with the development ofrespiratory distress in late preterm neonat...

Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS. The variance of the risk of RDS in various races/ethnicities or monozygotic/dizygotic twins has suggested genetic influences on this disorder. So far, se...

acute respiratory distress syndrome (ards) is a complex disorder of heterogeneous etiologies characterized by a consistent, recognizable pattern of lung injury and a potentially devastating form of acute inflammatory lung injury with a high short-term mortality rate and significant long-term consequences among survivors. recently, the new definition of ards has been published, and this definiti...

Current modalities of ventilatory assistance in the management of respiratory distress syndrome (RDS) in preterm infants range from continuous positive airway pressure (CPAP) to various modes of mechanical ventilation. The use of CPAP has been associated with a lower incidence of chronic lung disease when used as the initial respiratory support. In contrast, mechanical ventilation has the poten...

The observation that a raised venous pressure appears to be of benefit to newborn babies with respiratory distress (Bonham Carter, Bound, and Smellie, 1956) led Bound, Harvey, and Bagshaw (1962) to assess the effect of delayed clamping of the umbilical cord of premature babies. In that investigation it was concluded that the placental transfusion was responsible for the lower incidence of respi...

OBJECTIVE To determine the risk factors for persistent pulmonary hypertension of newborns (PPHN) and their influence on mortality. METHODS This was an observational study conducted at The Children's Hospital & the Institute of Child Health, Multan, Pakistan, from July 2011 to June 2012.All admitted babies who had respiratory distress, cyanosis and evidence of hypoxia on ABG,s were diagnosed p...

neonates with respiratory distress syndrome (rds), who are treated according to insure protocol; require arterial blood gas (abg) analysis to decide on appropriate management. we conducted this study to investigate the validity of pulse oximetry instead of frequent abg analysis in the evaluation of these patients. from a total of 193 blood samples obtained from 30 neonates <1500 grams with rds,...

large preterm infants are generally not considered good candidates for surfactant treatment until they have been intubated for progressing respiratory distress. this study has been done to detect the effect of electively providing early single-dose surfactant to large preterm babies with mild to moderate respiratory distress syndrome (rds). a randomized clinical trial was performed on 45 infant...

Background: The cornerstone of the treatment of respiratory distress syndrome (RDS) is respiratory support and surfactant replacement therapy. The administration of surfactant through a thin intratracheal catheter is one of the methods used to reduce one of the standard technique complications of a surfactant injection (Intubation-Surfactant-Extubation method [INSURE]). The aim of this study wa...