BACKGROUND AND OBJECTIVES Multidrug-resistant gram-negative bacteria are rapidly spreading throughout the world. The epidemiology of multidrug-resistant gram-negative bacteria in patients who require chronic hemodialysis has not been previously studied. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A prospective cohort study of an outpatient hemodialysis unit was conducted. Serial surveillanc...

BACKGROUND Vancomycin-resistant enterococci pose an emerging health risk. The limitation in therapeutic options has resulted in the development of new drugs such as quinupristin/ dalfopristin and linezolid. AIM, SETTING AND DESIGN: This study investigated the species prevalence and antibacterial resistance among enterococci isolated in selected Tehran hospitals. MATERIALS AND METHODS Between ...

Land application of manure from tylosin-treated swine introduces tylosin, tylosin-resistant enterococci, and erythromycin resistant rRNA methylase () genes, which confer resistance to tylosin. This study documents the persistence and transport of tylosin-resistant enterococci, genes, and tylosin in tile-drained chisel plow and no-till agricultural fields treated with liquid swine manure in alte...

s: Background: Multidrug-resistant Enterococci are major problem and are increasingly reported worldwide. Enterococcal infections have been associated with higher hospitalization costs and a higher number of related deaths. Treatment of multidrug-resistant enterococci has become a challenge in hospitals around the world due to the lack of reliable therapeutic options. So the present study was u...

The comparative in vitro activity of RU 64004 (also known as HMR 3004), a new ketolide antibiotic, was tested by agar dilution against approximately 500 gram-positive organisms, including multiply resistant enterococci, streptococci, and staphylococci. All streptococci were inhibited by < or = 1 microg of RU 64004 per ml. The ketolide was more potent than other macrolides against erythromycin A...