Background & Aims: Hypertension, hyperuricaemia and nephrotoxicity are some common side-effects of Cyclosporine A (CsA) treatment in renal transplant recipients. Previous studies suggest that Calcium Channel Blockers (CCB) can increase serum level of CsA and may improve graft function in patients receiving CsA. The aim of this study was to evaluate the effects of Diltiazem and Amlodipine on cyc...

Chronic exposure to lead is associated with adverse effects on renal function in laboratory animals and man. There is controversy concerning the direction of change of renal function parameters following chronic lead intoxication. The renal effects of low-dose lead exposure, as opposed to acute and pharmacological doses, require further scrutiny. In order to determine the effect of prolonged lo...

a male patient with acute renal failure (arf) due to large b-cell non-hodgkin lymphoma infiltration of kidney is presented. the diagnosis was suspected because of coincidence of arf and tumor lysis syndrome non-responsive to conservative renal therapies. a renal biopsy confirmed diagnosis and appropriate chemotherapy led to complete improvement of renal function.

the present study was aimed to evaluate the beneficial effect of cystone syrup in an experimental model of glycerol-induced acute renal failure (arf) in rats. biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of cystone syrup. administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...

The aim of this study was to explore if estimates of renal function could explain variability of (123)I-metaiodobenzylguanidine ((123)I-MIBG) assessed myocardial sympathetic activity. Furthermore estimates of renal function were compared to (123)I-MIBG as predictors of cardiac death in chronic heart failure (CHF). Semi-quantitative parameters of (123)I-MIBG myocardial uptake and washout were ca...

Dabigatran is a direct thrombin inhibitor that reduces the risk of systemic embolism in patients with nonvalvular atrial fibrillation. We report a case of an elderly man who developed unexplained rapid decline in renal function 6 weeks after starting dabigatran. A renal biopsy was planned to find out the etiology of acute renal failure, but the patient has significantly prolonged coagulation pa...

OBJECTIVE In patients with coronary artery disease, the concomitant presence of renal function impairment is associated with decreased survival. We aimed to assess whether in coronary artery diseased patients renal function impairment is associated with systemic vascular function, functional parameters of the renin-angiotensin system, or inflammation as potential mediators for cardiovascular ri...