Spin relaxometry with nitrogen-vacancy (N-$V$) centers in diamond offers a spectrally selective, atomically localized, and calibrated measurement of microwave-frequency magnetic noise, presenting versatile probe for condensed-matter biological systems. Typically, relaxation rates are estimated curve-fitting techniques that do not provide optimal sensitivity, often leading to long acquisition ti...

Background While cardiac involvement including heart failure represents the first cause of mortality in idiopathic inflammatory myopathies (IM), subclinical alterations may be largely underdiagnosed by conventional tests. CMR T1 mapping may provide more sensitive diagnostic markers of cardiac involvement in both acute and chronic phases in IM irrespective of cardiac function or late gadolinium ...

The properties of fluids saturating rocks depend strongly on temperature and pressure. Therefore, ambient laboratory conditions may not be desirable for the investigation of fluids in reservoir rocks. To mimic the reservoir, a pressurized and temperature controlled (overburden) cell, compatible with Nuclear Magnetic Resonance (NMR), was assembled within a 2 MHz NMR Rock Core Analyzer. 1D NMR re...

Scaling relationships are identified between NMR longitudinal relaxation times and clay dispersion quality in polymer-paramagnetic clay nanocomposites. Derived from a previously published analytical relationship developed from a lamella-based model, the scaling relationships are based on the enhancement of NMR relaxation rates with increasing exfoliation and dispersion homogeneity. The paramagn...

Fast Field-Cycling (FFC) is a technique used in NMR since the 1970s [1], and more recently in MRI [2]. It involves changing the strength of the main magnetic field during the pulse sequence, typically during polarisation, evolution and detection. FFC NMR offers many possibilities since it allows using low evolution fields to investigate the dispersion of the relaxation rate (R1), and switching ...

The purpose of this study was to determine the effects of intense exercise on the proton transverse (T(2)) relaxation of human skeletal muscle. The flexor digitorium profundus muscles of 12 male subjects were studied by using magnetic resonance imaging (MRI; 6 echoes, 18-ms echo time) and in vivo magnetic resonance relaxometry (1,000 echoes, 1.2-ms echo time), before and after an intense handgr...

Gd-EOB-DTPA, a liver-specific contrast agent with T1-shortening effects, is routinely used in clinical routine for detection and characterization of focal liver lesions and has recently received increasing attention as a tool for the quantitative analyses of liver function. We report the relationship between the extent of Gd-EOB-DTPA- induced T1 relaxation and the degree of liver fibrosis, whic...

INTRODUCTION The existence of partial volume effects in brain MR images makes it challenging to understand physio-pathological alterations underlying signal changes due to pathology across groups of healthy subjects and patients. In this study, we implement a new approach to disentangle gray and white matter alterations in the thalamus and the basal ganglia. The proposed method was applied to a...