Software aging often affects the performance of a software system and eventually causes it to fail. A novel approach to handle transient software failures is called software rejuvenation which can be regarded as a preventive and proactive solution that is particularly useful for counteracting the phenomenon of software aging. In this paper, we consider the optimal software rejuvenation policy m...

Restoring adult stem cell function provides an exciting approach for rejuvenating the aging brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive. Here we report that the enzyme ten eleven translocation methylcytosine dioxygenase 2 (Tet2), which catalyzes the production of 5-hydroxymethylcytosine (5hmC), rescues age-related decline in adult neurogenesis and enhan...

Maturation in conifers includes several distinct and persistent changes in the growth habits of apical meristems. Despite many studies on maturation in conifers, there are still many aspects of the process that have not been elucidated. For example, it is not known why maturation of cotyledon-derived tissue culture plantlets is rapid, whereas the natural maturation process is gradual. Also, it ...

This paper examines comprehensive evaluation of aperiodic time-based checkpointing and rejuvenation schemes maximizing the steady-state system availability in an operational software system. We consider two kinds of maintenance policies: checkpointing prior to rejuvenating (CPTR) and rejuvenating prior to checkpointing (RPTC). These schemes are complementary from each other to schedule checkpoi...

Zircon ages and trace element compositions from recent silicic eruptions in the Lassen Volcanic Center (LVC) allow for an evaluation of the timing and conditions of rejuvenation (reheating and mobilization of crystals) within the LVC magmatic system. The LVC is the southernmost active Cascade volcano and, prior to the 1980 eruption of Mount St. Helens, was the site of the only eruption in the C...

In Rigveda Soma is an evergreen plant, with thousand stalks yellow hued bestowing auspicious energy. Resembling yellow fibres of hemp ephedra was rained in Chlnoso Ho-Ma, Yellow-hemp. It was Sanskritized as Soma. Being an energizer-cum-euphoriant its juice was consumed thrice daily. Finally it became a drug of longevity, rejuvenation and resurrection even god Soma. As drug it was substituted by...

P eriorbital rejuvenation is a topic of particular interest to aesthetic surgeons, as aging changes often occur first around the eyelids, and periorbital surgery can improve both function and cosmesis. Ahead, the authors describe an approach to the periorbital aesthetic unit to treat the eyebrow, upper eyelid, lateral canthus, lower eyelid, and midface through a single upper eyelid blepharoplas...

Environmental policy is one of the key management dimensions of rejuvenation strategies in mature tourism destinations. Among these, voluntary environmental initiatives are increasingly becoming a relevant theoretical possibility and are an empirical reality. Voluntary environmental initiatives are primarily undertaken in developed countries, mostly in Europe, that is on itself a mature tourism...