Peripheral nerve long gap defects are a clinical challenge in the regeneration field. Despite the wide variety of surgical techniques and therapies, autografting is the "gold standard" for peripheral nerve gap reconstruction. The pathological process of Wallerian degeneration from the time of acute injury to efficient regeneration requires several weeks. Regeneration time is critical for nerve ...

The regenerating digit tip of mice is a novel epimorphic response in mammals that is similar to fingertip regeneration in humans. Both display restricted regenerative capabilities that are amputation-level dependent. Using this endogenous regeneration model in neonatal mice, we have found that noggin treatment inhibits regeneration, thus suggesting a bone morphogenetic protein (BMP) requirement...

Limb regeneration is observed in certain members of the animal phyla. Some animals keep this ability during their entire life while others lose it at some time during development. How do animals regenerate limbs? Is it possible to find unifying, conserved mechanisms of limb regeneration or have different species evolved distinct means of replacing a lost limb? How is limb regeneration similar o...

Simultaneous demultiplexing and regeneration of 40-Gb/s optical time division multiplexed (OTDM) signal based on self-phase and cross-phase modulation in a dispersion shifted fiber is numerically and experimentally investigated. The optimal walkoff time between the control pulse and OTDM signal is obtained by numerical simulation. Our experiment also shows that it is an effective method for rea...

The identification of an ecological niche specific to the regeneration phase has mobilised significant attention. However, the importance of the regeneration niche concept remains unclear. Our main objective was to study the existence of such a regeneration niche for a leguminous shrub, Ulex europaeus. This study was carried out in southwest France in the context of water and nutrient stresses ...

In this, the final issue of 2008 witch contains two issues (7 and 8), I would like to take this opportunity to thank those people who have contributed so much of their time and expertise in the interest of maintaining the highly respected reputation of the Journal. The topics to be covered are multiple sclerosis, Parkinson’s disease, spinal cord regeneration, TBI, and functional outcome researc...

Synopsis Sponges, simple and homogeneous relative to other animals, are particularly adept at regeneration. Although regeneration may appear to be obviously beneficial, and many specific advantages to regeneration of lost portions have been demonstrated, comparisons of regeneration among species of sponges have consistently revealed substantial differences in style (i.e., relative rates of reco...

Sponges, simple and homogeneous relative to other animals, are particularly adept at regeneration. Although regeneration may appear to be obviously beneficial, and many specific advantages to regeneration of lost portions have been demonstrated, comparisons of regeneration among species of sponges have consistently revealed substantial differences in style (i.e., relative rates of reconstitutin...

establishment of an efficient and reproducible regeneration protocol is one of the basic prerequisites for genetic transformation of any crop plant. in vitro culture of lentil has proven to be difficult. in spite of a number of reports on the regeneration of this plant, very few satisfying and reproducible protocol has yet been reported. this study carried out for investigation of different hor...