High-throughput siRNA screens are now widely used for identifying novel drug targets and mapping disease pathways. Despite their popularity, there remain challenges related to data variability, primarily due to measurement errors, biological variance, uneven transfection efficiency, the efficacy of siRNA sequences, or off-target effects, and consequent high false discovery rates. Data variabili...

We have demonstrated significant evidence of a solvent-dependent synthesis of hierarchical Cu7S4 polycrystalline nanocage assemblies with controllable aggregation-based building blocks by a sacrificial Cu2O template approach. The formation of a hierarchical Cu7S4 polycrystalline nanocage is essentially determined by a Kirkendall effect, which is attributed to the tailored-aggregation behaviour ...

Mg–Zn–Y ternary alloys containing the long-period stacking ordered (LPSO) phase exhibit superior mechanical properties. This is believed to be originating from LPSO acting as strengthening phase. However, we first clarify that properties of matrix Mg solid solution in Mg/LPSO two-phase alloy are significantly different those pure Mg. The yield stress a Mg99.2Zn0.2Y0.6 single crystal (matrix sol...

Surface strain tuning in a coupled heterostructure efficiently engineers the catalytic performance of heterogeneous catalysts by altering electronic structures and boosting electron transport. Generally, Bi-based are more favorable than ZnO for CO2 electroreduction to formate, but Bi is much costly Zn. Herein, new Bi2O2CO3/ZnO heterojunction catalyst with porous nanoplate morphology synthesized...

2D metal–organic frameworks are attractive filler in mixed matrix membranes (MMMs) due to the high aspect ratio and contact opportunity at filler–polymer interface. However, their alignment polymer remains a challenge fully play functions. Herein, our best knowledge, for first time, facile synthesis of KAUST-7-NH2 (KAUST, King University Science Technology) nanoplate is reported with 1D channel...

In this paper, buckling and free vibration analysis of a circular tapered nanoplate subjected to in-plane forces were studied. The linear variation of the plate thickness was considered in radial direction. Nonlocal elasticity theory was employed to capture size-dependent effects. The Raleigh-Ritz method and differential transform method were utilized to obtain the frequency equations for simpl...

Microwave irradiation can intensify catalytic chemistry by selective and controlled microwave-catalytic packed-bed interaction. However, turning it to reality from laboratory practical applications is hindered challenges in the reactor design scale-up. Here, we present a novel, rectangular traveling-wave microwave (RTMR) provide an easy-to-handle, 3-step procedure of such reactor. The multiphys...

Au@Cu2O cuboctahedron with gold triangular nanoplate core and Cu2O shell was synthesized by a chemical method. X-ray diffraction (XRD) and transmission electron microscopy (TEM) tests demonstrated that the as-synthesis samples were consisted of gold triangular nanoplate core and Cu2O shell, and both of them were in good crystallization. The effective size control of the particles could be reali...

Recent reports of the synthesis and assembly of faceted nanoplates with a wide range of shapes and composition motivates the possibility of a new class of two-dimensional materials with specific patterns targeted for a host of exciting properties. Yet, studies of how nanoplate shape controls their assembly - knowledge necessary for their inverse design from target structures - has been performe...