نتایج جستجو برای: rectal administration
تعداد نتایج: 263050 فیلتر نتایج به سال:
OBJECTIVE To determine the relative bioavailability and tolerability of a topiramate (TPM) suspension after rectal administration. DESIGN/METHOD Seven healthy men and five healthy non-pregnant women were enrolled. A 100 or 200 mg tablet of TPM was given orally and a 200 mg dose was given rectally in a randomized, open-label, crossover study with at least a 2-week washout period between doses....
Plasma concentration was measured after rectal and nasogastric administration of paracetamol 15 mg/kg to 28 febrile children aged between 9 days to 7 years who had undergone cardiac surgery. After equivalent doses, rectal administration in neonates and children on the first postoperative day was found to produce plasma concentrations below the therapeutic range with higher concentrations after ...
Abstract Background This study aimed to identify socioeconomic predictors of permanent stoma in rectal cancer treatment and examine its association with length stay at the facility. Methods Rectal patients who underwent elective surgery between January 2015 December 2018 were identified from Agency for Health Care Administration Florida Hospital Inpatient Discharge Dataset. Multivariate regress...
The absorption of diazepam after rectal administration was studied in children with epilepsy. When given as a solution, diazepam was rapidly absorbed and produced serum diazepam concentrations above 200 ng/ml within 10 minutes in most children. However, a commercial suppository formulation was absorbed slowly and cannot be recommended for urgent treatment of fits. There is a need in the UK for ...
Tiif, rectal route for anaesthesia has been long under consideration. The first efforts in this direction were made by F. Roux in1846. The undeniable advantages of the rectal route, the easiness of administration, the avoidance of choking and excitation, and freedom from complications, opened up the way for further research. Injury to the bowel wall was the great danger in the experiments of Ro...
background post laparoscopic cholecystectomy pain management can reduce recovery and discharge time. non-steroidal anti-inflammatory drugs and opioids are used for this purpose. objectives this randomized clinical trial evaluates the efficacy of diclofenac rectal suppository for the management of postoperative pain. patients and methods forty four patients were randomized to receive either 100 ...
To achieve successful delivery of drug locally as well as systematically rectal route has proved its potential. The main objective of this research work was to evaluate the in vivo performance of paracetamol Suppocire CP suppository. Initially, suppositories were prepared, evaluated for their physicochemical parameters and in vitro drug release. An in vivo investigation of paracetamol availabil...
Tenofovir gel is being evaluated for vaginal and rectal pre-exposure prophylaxis against HIV transmission. Because this is a new prevention strategy, we broadly assessed its effects on the mucosa. In MTN-007, a phase-1, randomized, double-blinded rectal microbicide trial, we used systems genomics/proteomics to determine the effect of tenofovir 1% gel, nonoxynol-9 2% gel, placebo gel or no treat...
Endoscopic ultrasound is recommended for rectal cancer staging. Transrectal ultrasound approach is able to overcome one of the limitations of this technique regarding circumferential rectal stenosis. Prior intrarectal administration of a small amount of fluid contrast agent optimizes the method, making it easier to distinguish the layers of the rectal wall and tumor formation. Endoscopic ultras...
OBJECTIVES There is a little data about rectal administration of Ketamine as a postoperative analgesic, so we compared the efficacy of rectal ketamine with rectal acetaminophen, which is applied routinely for analgesia after painful surgeries like tonsillectomy. METHODS In this single-blinded comparative trial, we enrolled 70 children undergoing elective tonsillectomy, and divided them random...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید