نتایج جستجو برای: received skin dose

تعداد نتایج: 752644  

abbas haghparast, Mahdi Mohammadi Razieh Zaghian

Introduction: Due to the prevalence of skin problems in patients after radiotherapy, skin dose measuring is importance. Content: Skin in vivo dosimetry means measuring the patient's (or phantom) skin dose during radiotherapy. According to the ICRP 59, the dose at the depth of 0.07 mm is known as a skin dose. The most radiosensitive epidermis cells are located...

Journal: :Cancer research 2011
Arijit Chakravarty Vaishali Shinde Josep Tabernero Andres Cervantes Roger B Cohen E Claire Dees Howard Burris Jeffrey R Infante Teresa Macarulla Elena Elez Jordi Andreu Edith Rodriguez-Braun Susana Rosello Margaret von Mehren Neal J Meropol Corey J Langer Bert ONeil Douglas Bowman Mengkun Zhang Hadi Danaee Laura Faron-Yowe Gary Gray Hua Liu Jodi Pappas Lee Silverman Chris Simpson Bradley Stringer Stephen Tirrell Ole Petter Veiby Karthik Venkatakrishnan Katherine Galvin Mark Manfredi Jeffrey A Ecsedy

The mitotic kinase Aurora A is an important therapeutic target for cancer therapy. This study evaluated new mechanism-based pharmacodynamic biomarkers in cancer patients in two phase I studies of MLN8054, a small-molecule inhibitor of Aurora A kinase. Patients with advanced solid tumors received MLN8054 orally for 7 consecutive days in escalating dose cohorts, with skin and tumor biopsies obtai...

Journal: :The New England journal of medicine 2014
G Ralph Corey Heidi Kabler Purvi Mehra Sandeep Gupta J Scott Overcash Ashwin Porwal Philip Giordano Christopher Lucasti Antonio Perez Samantha Good Hai Jiang Greg Moeck William O'Riordan

BACKGROUND Oritavancin is a lipoglycopeptide with bactericidal activity against gram-positive bacteria. Its concentration-dependent activity and prolonged half-life allow for single-dose treatment. METHODS We conducted a randomized, double-blind trial in which adults with acute bacterial skin and skin-structure infections received either a single intravenous dose of 1200 mg of oritavancin or ...

C. Yavas, G. Yavas, H. Acar, O. Ata, O.V. Gul,

Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...

A. Afzali, A.A. Mowlavi, N. Afzali,

Background: Skin cancer can be treated by various methods. Electron radiotherapy has been a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. Depth dose distribution of 166Ho using VARSKIN2 code is presented in this work. Material and Methods: Depth dose distribution of 166Ho was calculated, using VARSKIN2 code by adding...

ذبیح‌زاده, منصور, شمس, نسیم, غلامی, مهرداد, کرمی, وحید,

Background: Anode heel effect refers to reduction of radiation intensity in the anode side of X-ray tube. This variation in radiation intensity across the anode-cathode of X-ray tube can be benefited for decrease radiation exposure in some radiological examinations. The aim of this study was to evaluate the effect of anode heel orientation on the radiation dose received by the testes in male pa...

A male patient in his 20s presented at our clinic with pain caused by bone metastases of the primitive neuroectodermal tumor, and Sr-89 was administrated to palliate the pain. After receiving the injection, the patient complained of a slight burning pain at the catheterized area. Slight reddening and small circular swelling (diameter, 0.5 cm) were observed at the catheterized area. Sr-89 extrav...

2014
Wolfgang Pfützner Markus Rose Nils Nilles

Methods and results A 75-year old male suffering from erysipelas received simultaneous treatment with oral clindamycin and i.v. penicillin G, which later was switched to oral penicillin. After eight days of antibiotic therapy an erythematous maculopapular exanthema developed on his trunk and extremities. Treatment was changed to cefuroxime, topical steroids initiated and the skin rash slowly va...

Journal: :Journal of investigational allergology & clinical immunology 2014
G Noh E H Jang

BACKGROUND Specific oral tolerance induction (SOTI) for IgE-mediated food allergy (IFA) can be successfully achieved using interfero gamma (classic SOTI). OBJECTIVE In this study, a tolerable dose was introduced during tolerance induction with interferon gamma (dual SOTI), and its effectiveness was evaluated. METHODS The study population comprised 25 IFA patients. Blood samples were taken f...

Journal: :acta medica iranica 0
gholamreza eshghi department of dermatology, psoriasis research center, farshchian hospital, hamadan university of medical sciences, hamadan, iran. leila khezrian department of dermatology, psoriasis research center, farshchian hospital, hamadan university of medical sciences, hamadan, iran. fariba esna ashari department of dermatology, psoriasis research center, farshchian hospital, hamadan university of medical sciences, hamadan, iran.

melasma is a common acquired skin disorder. while different treatments are currently being used, in many cases it is refractory to treatment. according to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this new method for treatment of melasma. a total of 42 women with facial melasma, admitted to the department of dermatology of hamadan, were enrolled...

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