نتایج جستجو برای: rearrangement energettc material

تعداد نتایج: 390784  

Journal: :Frontiers in bioscience 2015
Manvendra Saxena Peter M Smooker Peter J Coloe

One of the ancient methods for the generation of bacterial mutants was to insert the composite transposable elements (e.g. Tn10) flanked by desired gene sequences, into the bacterial chromosome. This mechanism of DNA integrating into a chromosome can sometimes not only lead to the creation of desired mutants but also induced other recombination event within the chromosome. Several studies have ...

Journal: :Journal of computational biology : a journal of computational molecular cell biology 2007
Zheng Fu Xin Chen Vladimir Vacic Peng Nan Yang Zhong Tao Jiang

The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various biological problems critically rely on bona fide orthologs as input. While it is usually done using sequence similarity search, we recently proposed a new combinatorial approach that combines sequence similarity and ...

Journal: :Neoplasia 2014
Mirjam Blattner Daniel J Lee Catherine O'Reilly Kyung Park Theresa Y MacDonald Francesca Khani Kevin R Turner Ya-Lin Chiu Peter J Wild Igor Dolgalev Adriana Heguy Andrea Sboner Sinan Ramazangolu Haley Hieronymus Charles Sawyers Ashutosh K Tewari Holger Moch Ghil Suk Yoon Yong Chul Known Ove Andrén Katja Fall Francecsa Demichelis Juan Miguel Mosquera Brian D Robinson Christopher E Barbieri Mark A Rubin

BACKGROUND Recurrent mutations in the Speckle-Type POZ Protein (SPOP) gene occur in up to 15% of prostate cancers. However, the frequency and features of cancers with these mutations across different populations is unknown. OBJECTIVE To investigate SPOP mutations across diverse cohorts and validate a series of assays employing high-resolution melting (HRM) analysis and Sanger sequencing for m...

Journal: :Haematologica 2006
Alberto Zamò German Ott Tiemo Katzenberger Patrick Adam Claudia Parolini Aldo Scarpa Maurizio Lestani Fabio Menestrina Marco Chilosi

BACKGROUND AND OBJECTIVES Mantle cell lymphoma (MCL) cell lines are difficult to generate; only nine lines have been described so far and few of them have been thoroughly characterized. DESIGN AND METHODS We established MAVER-1, a new MCL cell line, obtained from a leukemic MCL harboring both a t(11;14) translocation and a MYC rearrangement, and used immunohistochemistry, flow cytometry, mole...

Journal: :The American journal of pathology 2001
U Lehmann O Bock F Länger H Kreipe

Assessment of clonality either by demonstrating light chain restriction or showing monoclonal immunoglobulin gene rearrangement is a valuable and indispensable adjunct to diagnosis in hematopathology. The study of light chain restriction by immunohistochemistry on archival material is hampered by a very low sensitivity especially regarding low grade lymphomas of B cell origin. DNA rearrangement...

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 1990
mohsen ghalamkar moazzam ahmad shaabani

rearrangement of propargyl amine salt, in the presence of a base was studied and it was concluded that this occurs through an allenic intermediate.

Journal: :Angewandte Chemie 2007
Eiji Tayama Hiroshi Kimura

The Stevens and Sommelet–Hauser rearrangement of ammonium ylides are known as useful transformations for organic synthesis because they convert a readily accessible C–N bond into a new C–C bond. The Stevens rearrangement has been widely used for the asymmetric synthesis of α-amino acid derivatives, whereas the Sommelet–Hauser rearrangement is much less common because the Sommelet–Hauser rearran...

Journal: :Journal of Synthetic Organic Chemistry, Japan 1986

Journal: :Journal of Synthetic Organic Chemistry, Japan 1966

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