Cerebral spinal fluid (CSF) and structural imaging markers are suggested as biomarkers amended to existing diagnostic criteria of mild cognitive impairment (MCI) and Alzheimer's disease (AD). But there is no clear instruction on which markers should be used at which stage of dementia. This study aimed to first investigate associations of the CSF markers as well as volumes and shapes of the hipp...

A new methodology for classification of MR images is proposed using a large data base (more than one thousand patient), for the classification of MCI patients, especially in the case of MCI-C and MCI-NC, using simultaneously all kind of features is proposed. An important goal in this paper is the identification and classification between normal subjects, MCI (Middle Cognitive Impairment) patien...

Although motion compensated interpolation (MCI) improves the vertical resolution of de-interlaced frames effectively, it often introduces serious defects like feathering artifacts. In this paper, we propose an arbitration rule between MCI and intra-field interpolation for de-interlacing to avoid the motion compensation artifacts (MCAs) produced by erroneous MCI. In the proposed deinterlacing me...

OBJECTIVES To examine the incidence of dementia in subjects with mild cognitive impairment (MCI) in the Cardiovascular Health Study Cognition Study. DESIGN Prospective epidemiological study. SETTING The Cardiovascular Health Study Cognition Study of Pittsburgh, Pa, was conducted from 2002 through 2003 to determine the incidence of dementia in participants classified as having MCI in 1998 an...

use Abstract: This review addresses the literature surrounding Parkinson’s disease (PD) and mild cognitive impairment (MCI). It discusses the neuropsychological, pharmaceutical, and pathological overlap, the socioeconomic impact of PD and MCI, and the value of recognizing, understanding, and treating MCI in PD. It is concluded from this review that MCI in PD does exist and should be considered ...

Background: Various studies have documented age-related changes in cognitive abilities and neural basis. Objectives: To investigate the role of neuropsychological function tests in predicting amnestic mild cognitive impairment in the elderly. Materials & Methods: In this cross-sectional study with a correlational design, the study population included elderly people over 60 years old residing ...

Psychiatric symptoms/syndromes are frequent in Mild Cognitive Impairment (MCI). However, only a few studies reported full psychiatric diagnoses in MCI. We describe the nosology and prevalence of psychiatric diagnoses in a group of 102 consecutive patients evaluated for suspected MCI and finally re-classified into dementia, MCI and No Cognitive Impairment. Psychiatric diagnoses were frequent in ...

Heart fatty acid binding protein (HFABP) has been proposed as a putative marker for dementia disorders. To evaluate the value of this protein as an early marker of Alzheimer's disease (AD), we analyzed HFABP level and the classical biomarkers amyloid-β (Aβ)1-42, total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF) of patients with mild cognitive impairment (MCI) follow...