Background Intrusive reactive strategies (physical restraint, emergency medication and seclusion) are frequently used procedures in the management of challenging behaviour. The present study identifies predictors for reactive strategy use in an attempt to more clearly delineate at risk service users. Method Eight hundred and thirty-nine agencies and service settings in a large area of South Wal...

A correlation of clinical, MRI, and neuropathological data is reported in two patients with multiple system atrophy (MSA). On MRI, patient 1 showed striatal atrophy, reduction of T2 relaxation times within most of the putamen, and a band of hyperintense signal changes in the lateral putamen. In patient 2, MRI disclosed only shortening of the T2 signal in the putamen. Immunohistochemistry showed...

Users of today’s popular wide-area apps (e.g., Twitter, Google Docs, and Words with Friends) must no longer save and reload when updating shared data; instead, these applications are reactive, providing the illusion of continuous synchronization across mobile devices and the cloud. Achieving this illusion poses a complex distributed data management problem for programmers. This paper presents t...

There are a wide variety of reactive species which can affect cell function, including reactive oxygen, nitrogen, and lipid species. Some are formed endogenously through enzymatic or non-enzymatic pathways, and others are introduced through diet or environmental exposure. Many of these reactive species can interact with biomolecules and can result in oxidative post-translational modification of...

Active real-time databases have emerged as a research area in which concepts of active databases and real-time databases are combined into a real-time database with reactive behavior. However, this marriage is not free from complications. The main problem is that timeliness, i.e., predictability and eeciency, is of paramount importance in real-time databases, while reactive behavior may add to ...

Dynamical systems working have been recognized as essential in the area of computer science, under the name of reactive systems by David Harel. Synchronous languages have been proposed as a paradigm to deal with reactive systems and develop tools for them. In this paper we introduce synchronous programming paradigm via the notion of multiclock dynamical systems and illustrate it via the SIGNAL ...

Dynamical systems working have been recognized as essential in the area of computer science, under the name of reactive systems by David Harel. Synchronous languages have been proposed as a paradigm to deal with reactive systems and develop tools for them. In this paper we introduce synchronous programming paradigm via the notion of multiclock dynamical systems and illustrate it via the SIGNAL ...

Background Clostridium difficile infection (CDI) is a common cause of antibiotic-associated diarrhea and can be difficult to cure. Most patients with CDI present only colonopathy and in fewer cases extra intestinal features were described such as reactive arthritis (ReA). We present a series of cases with CDI-associated reactive arthritis (CDI-AReA), admitted between 2011-2014 in the National I...