Methanolic extracts from 15 medicinal plants representing 11 families, used traditionally for malaria treatment in Kenya were screened for their in vivo antimalarial activity in mice against a chloroquine (CQ)-tolerant Plasmodium berghei NK65, either alone or in combination with CQ. The plant parts used ranged from leaves (L), stem bark (SB), root bark (RB), seeds (S) and whole plant (W). When ...

The real-time dynamics of photoexcited and photoionized rubidium (Rb) atoms attached to helium (He) nanodroplets is studied by femtosecond pump-probe mass spectrometry. While excited Rb atoms in the perturbed 6p-state (Rb*) desorb off the He droplets, Rb(+) photoions tend to sink into the droplet interior when created near the droplet surface. The transition from Rb(+) solvation to full Rb* des...

In this paper, we introduce the notion of super finitely separating functions which gives a characterization of RB-domains. Then we prove that FS-domains and RB-domains are equivalent in some special cases by the following three claims: a dcpo is an RB-domain if and only if there exists an approximate identity for it consisting of super finitely separating functions; a consistent join-semilatti...

Inactivation of the retinoblastoma protein (Rb) has a key role in tumorigenesis. It is well established that Rb function is largely regulated by a dynamic balance of phosphorylation and dephosphorylation. Although much research has been done to understand the mechanisms and function of RB phosphorylation, the regulation of Rb dephosphorylation is still not well understood. In this study, we dem...

The recent finding that the Retinoblastoma protein (Rb) is able to regulate apoptosis in a non-transcriptional manner directly at the mitochondria by interaction with the pro-apoptotic protein Bax prompted this investigation of the complex formed between Rb and Bax. Because the function of Rb in the cellular processes of proliferation, apoptosis, senescence and differentiation is regulated by p...

In this paper, we propose two novel memoryless reverse converters for the moduli set {2 − 1, 2, 2 − 1}. The first proposed converter does not entirely cover the dynamic range while the second proposed converter covers the entire dynamic range. First, we simplify the Chinese Remainder Theorem in order to obtain a reverse converter that utilizes mod-(2 − 1) operation. Second, we further reduce th...

Background and Objectives: Power electronics infrastructures play an important role in charging different types of electric vehicles (EVs) especially Plug-in Hybrid EVs (PHEVs). Designing appropriate power converters is the topic of various studies. Method: In this paper, a novel bidirectional buck-boost multifunctional integrated converter is presented which is capable of handling battery and ...

the aim of this paper is to design a fractional order sliding mode controllers (fosmc)for a class of dc-dc converters such as boost and buck converters. firstly, the control lawis designed with respect to the properties of fractional calculus, the design yields an equiv-alent control term with an addition of discontinuous (attractive) control law. secondly, themathematical proof of the stabilit...

The E7 oncoprotein of human papillomavirus type 16 promotes cell proliferation in the presence of antiproliferative signals. Mutagenesis of E7 has revealed that this activity requires three regions, conserved regions 1 and 2 and a C-terminal zinc finger. Binding to the retinoblastoma tumor repressor (Rb) through an LxCxE motif in conserved region 2 is necessary, but not sufficient, for E7 to in...

This paper presents performance evaluation of an asymmetrical parameter type two-phase induction machine drive using two-phase three-leg voltage source converter (VSC) operating in motoring and generating modes. A system is simulated using MATLAB/SIMULINK. The proposed converter system includes a machine side converter using a three-leg VSC and a front end converter using a single-phase full br...