Peyronie’s disease is an idiopathic, localized connective tissue disorder of the penis, involving the tunica albuginea of the corpus cavernosum and adjacent areolar space. Current proposals as to the origin of Peyronie’s disease suggest that fibrosis and collagen changes of the tunica are the result of an inflammatory process following vascular trauma. Our laboratory and other investigators hav...

The first goal of this study was to examine the effect of secondhand smoking on neurogenic, endothelium- and cGMP-dependent relaxant responses of rabbit corpus cavernosum smooth muscle. Our second goal was to determine whether such an effect can be prevented by oral administration of L-arginine. Male New Zealand rabbits were divided into control, chronic passive cigarette smoking and L-arginine...

The objective of this study was to investigate structural changes in the penile corpus cavernosum of prepubertal chronically stressed rats. Eight Wistar rats were assigned into the stress group (SG) and were submitted to 2 hours of tube restraint daily, from the fourth to the ninth week of life. Another 7 rats were used as the control group (CG). All animals were weighed weekly. At day 64,...

OBJECTIVE This study was conducted to investigate the mechanisms of action of Eurycoma longifolia in rat corpus cavernosum. MATERIALS AND METHODS Tincture of the roots was concentrated to dryness by evaporating the ethanol in vacuo. This ethanolic extract was partitioned into 5 fractions sequentially with hexane, dichloromethane (DCM), ethyl acetate, butanol, and water. The corpus cavernosum ...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2016;5(S1) tau.amegroups.com apomorphine test. Then the animals were divided into three groups: (I) nondiabetic control groups, (II) diabetic rats + vehicle and (III) diabetic rats + MDL28170. Two weeks later the erectile function was measured by electrical stimulation of the cavernous nerve and the ratio between in...

BACKGROUND:Several investigations showed cartilaginouscells in fibrous tissue of the free part of the penis in one humpedcamel. OBJECTIVES: The aim of this study was accurate assessmentof existence of cartilaginous cells in penis shaft of onehumpedcamel. METHODS: Six camel penises from maturedcamels more than 3 years-old were collected from an abattoir.Different specimens were prepared from eac...

Introduction Abscess of the corpus cavernosum is an uncommon infection. Only 23 cases have been reported in the literature1. Precipitating factors include intracavernous injection therapy, foreign bodies, perianal abscess extension, priapism and bloodstream seeding from another primary site1. Diabetes is a major risk factor for cavernosal abscess due to the presence of microvascular disease and...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau corpus cavernosa in the horizontal direction. In the CD rat, we observed the tissue of the regenerated corpus cavernosa, the structure resembled that of the SH rat in appearance of HE-stained tissue. Immunohistochemical analysis revealed that, in the SH rat, vascular smooth muscles were ...