Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of genital Crohn’s disease (CD) is in the form of erythema and edema of the labia and scrotum. Here, we...

esophageal squamous cell carcinoma is a rather common cancer in northern iran. incidence of adenocarcinoma of esophagus has an increasing trend in iran. co-existence of both cancers in one patient is very rare. we report a middle age woman from northern iran with a typical presentation of esophageal cancer, who was found to have a dual esophageal cancer. the disease was found in the advanced st...

Laryngeal leiomysarcoma is an extremely rare malignancy originating from smooth muscle cells. Its rarity is due to the fact that only less than 50 cases of pure laryngeal leiomyosarcoma and less than 10 cases of hypopharyngeal leiomyosarcaoma have been reported in modern medical literature.  Even though the clinical presentation mimics that of a laryngeal carcinoma forming the major bulk of the...

manifestation of chorea in patients with systemic lupus erythematosus (sle) and antiphospholipid antibody syndrome (apa synd.) is not common. moreover, primary presentation of the disease with chorea is rare and only few such cases are reported in literature in recent years. we report here the case of a 28 year old woman who was first seen at the age of 10 with clinical manifestations of chorea...

cutaneous leishmaniasis(cl) is referred to a group of diseases because of the varied clinical presentation, ranging from small cutaneous nodule to wide spread mucosal destruction. the nose is rarely involved by cl in even in endemic region. in this report we describe a rare rhinophymatous presentation of cl from a non-endemic region which was diagnosed by fine needle sampling and treated with m...

  Primary leiomyosarcoma of the broad ligament is a very rare, rapidly progressive and highly malignant gynecological tumor and only 16 cases have been reported in the literature. Here, presentation of leiomyosarcoma of the left broad ligament in a 26-years-old woman is reported. Clinical presentation and histological diagnosis is discussed. The patient has been treated surgically and remains...