Blood ethanol concentrations after separate oral dosing and intravenous infusion of ethanol (0.15 g/kg) were measured in 16 control subjects and 13 subjects treated with ranitidine. All subjects underwent routine upper gastrointestinal endoscopy. Peak blood ethanol concentrations, and area under the blood ethanol/time curve, were significantly higher in the ranitidine group after oral, but not ...

A new spectrophotometric method is proposed for the assay of ranitidine hydrochloride (RNH) in bulk drug and in its dosage forms using ceric ammonium sulphate (CAS) and two dyes, malachite (MAG) green and crystal violet (CV) as reagents. The method involves the addition of a known excess of ceric ammonium sulphate to ranitidine hydrochloride in acid medium, followed by the determination of unre...

(Athena stands for abbreviation of Abstracting and Thoughtful Evaluation of Neonatal Articles; but it is also personified by the contributor. Like Athena of Greek mythology, she distills wisdom from published literature) Necrotizing enterocolitis (NEC) is a common surgical emergency in neonates. The list of etiological agents of NEC is already exhaustive. A recent paper published in Pediatrics ...

OBJECTIVES To determine the effectiveness of ranitidine and sucralfate in the prevention of stress ulcer in critical patients and to assess if these treatments affect the risk of nosocomial pneumonia. DESIGN Published studies retrieved through Medline and other databases. Five meta-analyses evaluated effectiveness in terms of bleeding rates (A: ranitidine v placebo; B: sucralfate v placebo) a...

Several studies have reported the presence of pharmaceuticals in freshwater bodies all around world. For this investigation, removal ciprofloxacin (CIP) ranitidine (RNT), and chlorphenamine (CPM) using lignocellulose-derived granular activated carbon (GAC) was analyzed, physicochemical mechanisms were elucidated. Additionally, textural surface properties GAC evaluated, concentrations contaminan...

Isolated bovine adrenocortical cells were incubated with and without 3 ng/ml ACTH, with various concentrations (10-1000 micrograms/ml) of either cimetidine or ranitidine. Cortisol, corticosterone, and deoxycorticosterone outputs were measured. Cimetidine and ranitidine at 320 and 1000 micrograms/ml inhibited ACTH-stimulated corticosterone and cortisol synthesis and cimetidine decreased basal co...

INTRODUCTION Captopril is an angiotensin-converting enzyme inhibitor, which is used as an antihypertensive agent and has shown antioxidant properties. This study aims at determining the effects of captopril on factors affecting gastric mucosal integrity in aspirin-induced gastric lesions. MATERIAL AND METHODS Eighteen male Sprague-Dawley (200-250 g) rats that were given aspirin (40 mg/100 g b...

Background: Since ranitidine inhibits the activity of testis Na+-K+ATPase, Ca++ATPase and Mg++ATPase enzymes, and affects estrogen metabolism in the liver and causes gynecomastia, the effects of long term use of ranitidine on testis were studied. Materials and Methods: In this experimental study 40 two-month aged male rats were divided into four groups (control group and 1, 2&3 test groups). T...

Thirty two consecutive patients (age range 6 months-13.4 years) with severe reflux oesophagitis were randomised to a therapeutic trial for eight weeks during which they received either standard doses of omeprazole (40 mg/day/1.73 m2 surface area) or high doses of ranitidine (20 mg/kg/day). Twenty five patients completed the trial (12 on omeprazole, 13 on ranitidine). At entry and at the end of ...