Large well-designed clinical efficacy and safety randomized clinical trials (RCTs) are required to achieve regulatory approval of new drug treatments. The objective of this article is to make recommendations for the criteria for defining and selecting the clinical trial study population, design and efficacy outcomes measures which comprise ideal premature ejaculation (PE) interventional trial m...

abstract background: premenstrual syndrome (pms) can cause problems in daily work and relationships. materials and methods: eighty‑six women were randomly assigned to two intervention groups and one control group. patients were asked to fill out the pms daily symptoms record for 2 months, and then the participants were randomly assigned to one of the three study groups. medical intervention was...

abstract backgrounds: subacromial impingement is a common cause of shoulder pain and many patients with this condition recover with conservative management. the most commonly used modalities of nonoperative treatment include activity modification, anti-inflammatory medication and subacromial injection of steroid and ultrasound and physical therapy programs. this study assessed the value of phys...