introduction: radioisotope scanning is the best method for objective assessment of salivary gland function. thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. methods: patients randomized in placebo-controlled trial of piloc...

ABSTRACTIntroduction: Radiotherapy is a cancer therapy that uses ionizing radiation to damage cells. Ionizing in the head and neck area can disrupt function integrity of oral mucosa cause mucositis. In Bandung, prevalence risk factors mucositis (HNC) patients undergoing radiotherapy have not been studied. Some textbooks claim radiotherapy-induced HNC occurs at almost 100%. Various associated wi...

background and aims. salivary glands are very susceptible to radiation and any disturbances in their function are detrimental to the hard tissues in the oral cavity. the aim of this study was to evaluate posterior class v dental caries in patients with head and neck cancers undergoing radiotherapy. materials and methods. in this study, twenty seven patients undergoing conventional radiotherapy ...

The present study compared the dose-volume histograms of patients with Stage IIIA non-small cell lung cancer (NSCLC) treated with carbon ion radiotherapy with those of patients treated with X-ray radiotherapy. Patients with Stage IIIA NSCLC (n = 10 patients for each approach) were enrolled. Both radiotherapy plans were calculated with the same targets and organs at risk on the same CT. The trea...

Introduction: Radioisotope scanning is the best method for objective assessment of salivary gland function. Thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. Methods: Patients randomized in placebo-controlled trial of...

Unfortunately, last winter, we lost one of the leaders of Radiotherpy-Oncology in Iran, Professor Mohammad Hossein Salehi. He was an excellent teacher, a supportive friend and an experienced physician.Professor Salehi was born on April 21, 1941 in Shirvan. After graduating from high school, he continued his education in Mashhad Medical School. In 1968 he completed Medical School and began the R...

Background: Human beta-defensins (hBDs) are small cationic peptides of the epithelium with broad antimicrobial and immune response-regulatory activities. hBDs also related to oncogenesis, their secretion profiles affected by radiotherapy treatment. The present study aimed investigate oral cavity hBD 1-3 levels in head neck cancer patients its relation Methods: Sixteen (all a history smoking) we...

Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis subcutaneous tissue without systemic involvement. Radiation-induced morphoea rare, often unrecognised, chronically progressive form radiation-associated localised scleroderma skin, infrequently progressing to scleroderma. Systemic widespread along with features, leading an increased risk mal...

Radiochromic film has become an important tool to verify dose distributions in highly conformal radiation therapy such as IMRT. Recently, a new generation of these films, EBT3, has become available. EBT3 has the same composition and thickness of the sensitive layer of the previous EBT2 films, but its symmetric layer configuration allows the user to eliminate side orientation dependence, which i...

background: normal tissue toxicity continues to remain as a major challenge for radiation oncologists for delivering the total dose to the tumour cells in cancer patients. cellular, molecular and plasma based early biomarkers to predict the overreactions and non-overreactions of normal tissue toxicity before the initiation of radiotherapy can be valuable for personalised treatment. the aim of t...