A clinicopathological study was made on 45 autopsy cases of brain tumors treated with radiotherapy. Morphological changes after radiotherapy were classified into six categories : 1) tumor disappearance, 2) small residual tumor, 3) extensive tumor necrosis, 4) proliferative tumor growth, 5) mixed glioblastoma and fibrosarcoma, and 6) no remarkable change. When the tumors are primarily radiosensi...

Various aspects of the ultrastructure of the dividing nuclei in the large radiosensitive amoeba Pelomyxa illinoisensis are demonstrated. Evidence of nuclear envelope breakdown is presented, and membrane fragments are traced throughout metaphase to envelope reconstruction in anaphase and telophase. Annuli in the nuclear envelope and its fragments are shown throughout mitosis. During metaphase an...

A gel matrix (gelatin), infused with acrylamide monomer and a crosslinking agent has been used as a three-dimensional dosimeter of Xand c-rays as used in radiotherapy. Magnetic resonance imaging is used to create a parameter map of transverse relaxation time (1 2 ) from which a map of absorbed dose is calculated. We are using the technique to investigate the interfacial radiation patterns resul...

Background Patients' dosimetry is crucial in order to enhance radiation protection optimization and to deliver low radiation dose to the patients in a radiological procedure. The aim of this study was to assess the entrance surface dose (ESD) and radiation dose to the radiosensitive organs in pediatric pelvic radiography. Materials and Methods The studied population included 98 pediatric patien...

Numerous in vitro studies have shown that human cell lines lacking functional ATM are extremely radiosensitive. In this issue, Moding et al. demonstrate using a murine model of sarcoma that deletion of the Atm gene has much less of a radiosensitizing effect on normal cardiac endothelia than on rapidly proliferating tumor endothelia. This work confounds our assumptions about the generality of th...