نتایج جستجو برای: radioprotectors
تعداد نتایج: 159 فیلتر نتایج به سال:
Visible Diode Laser Enhancement of Exotic DNA Uptake by Fowl SpermEssam A. El-Gendy, Mona M. Abdelaziz, Mohamed Abdelfattah, S. Salama, YhiaM. Badr
Purpose: Discovery of agents that protect or mitigate normal tissue from radiation injury during radiotherapy, accidents, or terrorist attacks is of importance. Specifically, bone marrow insufficiency, with possible infection due to immunosuppression, can occur after total body irradiation (TBI) or regional irradiation and is a major component of the acute radiation syndrome. The purpose of thi...
Physico-Chemical Evaluation of Rationally Designed Melanins as Novel Nature-Inspired Radioprotectors
BACKGROUND Melanin, a high-molecular weight pigment that is ubiquitous in nature, protects melanized microorganisms against high doses of ionizing radiation. However, the physics of melanin interaction with ionizing radiation is unknown. METHODOLOGY/PRINCIPAL FINDINGS We rationally designed melanins from either 5-S-cysteinyl-DOPA, L-cysteine/L-DOPA, or L-DOPA with diverse structures as shown ...
Radiation oncologists have observed variation in normal tissue responses between patients in many instances with no apparent explanation. The association of clinical tissue radiosensitivity with specific genetic repair defects (Wegner's syndrome, Ataxia telangiectasia, Bloom's syndrome, and Fanconi anemia) has been well established, but there are unexplained differences between patients in the ...
Purpose: Discovery of agents that protect or mitigate normal tissue from radiation injury during radiotherapy, accidents, or terrorist attacks is of importance. Specifically, bone marrow insufficiency, with possible infection due to immunosuppression, can occur after total body irradiation (TBI) or regional irradiation and is a major component of the acute radiation syndrome. The purpose of thi...
BACKGROUND Radiotherapy of head and neck tumors often leads to acute reactions of the adjacent normal tissues resulting e.g. in mucositis and xerostomia. Therefore, radioprotective drugs have been developed to reduce these effects. Studies on a tumor model using amifostine and sodium selenite adjuvant to fractionated irradiation should show whether the radioprotective effect on normal tissue le...
protection of biological systems against radiation damage is of paramount importance during accidental and unavoidable exposure to radiation. several physico-chemical and biological factors collectively contribute to the damage caused by radiation and are, therefore, targets for developing radioprotectors. chemicals capable of scavenging free radicals, relieving oxidative stress, promoting anti...
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