The prevention of fractures amongst older people consists of (i) prevention and treatment of osteoporosis, (ii) prevention of falling and (iii) prevention of fractures using injury-site protection. As the great majority of hip fractures are caused by a sideways fall with direct impact on the greater trochanter of the proximal femur, one approach to prevention is the use of an adequately configu...

BACKGROUND The LMA Protector™ is the latest CE marked single use supraglottic airway device. This airway device provides access and functional separation of the respiratory and digestive tracts. There are two ports (male, female ports) to provide suction in the laryngeal region and insertion of the gastric tube. The aim of our study is to assess the ease of use, airway quality, device positioni...

OBJECTIVES To assess predictors of hip-protector use in nursing home residents under usual-care conditions and after intervention consisting of structured education of nurses and nursing home residents and provision of free hip protectors. DESIGN Nested cohort analyses within a cluster randomized, controlled trial with 18 months follow-up. SETTING Forty-nine nursing home clusters in Hamburg...

This paper investigates how formal techniques can be used for the analysis and veriication of hybrid systems 1,5,7,16] | systems involving both discrete and continuous behavior. The motivation behind such research lies in the inherent similarity of the hierarchical and decentralized control strategies of hybrid systems and the communication and operation protocols used for distributed systems i...

INTRODUCTION Among surgical oncology patients, incisional surgical site infection is associated with substantially increased morbidity, mortality and healthcare costs. Moreover, while adults undergoing pancreaticoduodenectomy with preoperative placement of an intrabiliary stent have a high risk of this type of infection, and wound protectors may significantly reduce its risk, no relevant studie...

Larval zebrafish (Danio rerio) of two different age classes ("swim-up" larvae, 9 days old; "free-swimming" larvae, 21 days old) were exposed to either an endurance/continuous training or interval training. Control animals were kept in stagnant water. A comparison of cardiac activity of trained (either endurance or interval) and untrained animals at the end of the training regime revealed no dif...

BACKGROUND AND AIMS Targeting the early mechanisms in exercise-induced arterial hypertension (which precedes resting arterial hypertension in its natural history) may improve cardiovascular morbidity and mortality in COPD patients. Capillary rarefaction, an early event in COPD before vascular remodeling, is a potential mechanism of exercise-induced and resting arterial hypertension. Impaired tr...

Objectives: A correlative study on data from 14 women with unilateral chronic shoulder pain was undertaken. Methods: Data were obtained on evoked pain and pressure-pain thresholds [PPTs] changes upon muscle exertion and biopsy findings on capillary density and muscular pathology. The PPTs were measured in the trapezius muscle, before and after a static abduction endurance test of the shoulder [...

Microvascular exchange in the liver is governed by fenestrations in sinusoidal endothelial cells and can be manipulated pharmacologically. Microvascular exchange is affected in alcoholic liver disease and cirrhosis, the former leading to a loss of fenestrae, the latter to sinusoidal capillarization and thereby to loss of liver function in disease.

House mice selectively bred for high voluntary wheel running display a mini-muscle (MM) phenotype wherein mass-specific mitochondrial enzyme activities are double that of normal, but muscle mass is reduced by half. In addition, mini-muscles are characterized by small muscle fibers in the superficial region of the plantaris and medial gastrocnemius muscles. To determine the structural alteration...