نتایج جستجو برای: quinazolinone

تعداد نتایج: 353  

Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...

Journal: :International Journal of Current Pharmaceutical Research 2020

2011
Abdelaaziz Ouahrouch Moha Taourirte Hassan B. Lazrek Mohamed El Azhari Mohamed Saadi Lahcen El Ammari

In the heterocyclic title compound, C(17)H(19)N(5)O(3), the quinazolinone ring system forms a dihedral angle of 67.22 (7)° with the triazole ring. The butyl acetate group has a non-linear conformation, with an alternation of synclinal and anti-periplanar torsion angles [N-C-C-C = 58.5 (2)°, C-C-C-C = 170.72 (19)° and C-C-C-O = -65.9 (3)°]. The crystal structure features inter-molecular C-H⋯N an...

2013
Chun-Yan An Xiao-Ming Li Chun-Shun Li Ming-Hui Wang Gang-Ming Xu Bin-Gui Wang

Four new quinazolinone alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa. The structures of the new compounds were elucidated by spectroscopic analysis, and their absolute configurations were determined on the basis of chiral HPLC an...

Journal: :European journal of advanced chemistry research 2023

A versatile and green synthetic protocol has been developed for synthesis of substituted quinazolinone spiroquinazolinone heterocycles effectively via a combined surfactant mediated system. The use Surfactant, water as reaction medium, room temperature, high yield ease purification made the process very effective ecofriendly in nature. To demonstrate wide scope Isatoic anhydride Isatin used rea...

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