In the present work, the synthesis and structural characterization of a 2-phenyl3(benzamido propyl) quinazoline (3H) -4one semicarbazone/ thiosemicarbazone hydrochloride and its metal complexes have been reported. All the synthesized compounds were characterized by using various physico-chemical techniques such as Infrared spectra, electronic spectra, molar conductivity and magnetic susceptibil...

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyland diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.

A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.

The title compound, C(21)H(21)N(5)O(2)·0.5H(2)O, has two fused six-membered rings linked to a benzene ring and to a triazole ring, which is connected to a butanol group. The quinazoline ring forms a dihedral angle of 7.88 (8)° with the benzene ring, while the triazole ring is approximately perpendicular to the benzene ring and to the quinazoline system, making dihedral angles of 84.38 (10) and ...

OBJECTIVES A series of 3(benzylideneamino)-2-phenyl quinazoline-4(3H)-ones was synthesized by reaction of 3-amino-2-phenyl-3H-quinazoline-4-one with various carbonyl compounds. MATERIALS AND METHODS Chemical structures of the synthesized compounds were confirmed by IR, 1H-NMR and mass spectral analysis. Title compounds were investigated for cytotoxicity and antiviral activity against herpes s...

Background: The largest infectious agent-related cause of death and the most common disease with a high contagiousness profile is tuberculosis. For treatment tuberculosis, various benzimidazole quinazoline compounds have been developed in past effectiveness. In this example, our goal was to synthesise new enhanced activity by combining moieties quinazoline. present study planned synthesize nove...