Purpose. Quantitative magnetization transfer imaging (qMTI) provides information on otherwise MR-invisible macromolecules via cross relaxation or proton exchange with water molecules. In cerebral white matter (WM), qMT parameters are assumed to be related to myelination and have been used as markers of WM pathology [1]. This is particularly true for the macromolecular pool-size fraction, M0b. I...

MRI is used routinely in clinical practice and pharmaceutical trials to measure disease activity and assess the effects of treatment in multiple sclerosis. Conventional MRI techniques sensitively detect inflammation, demyelination, and tissue injury. Less conventional imaging modalities, such as magnetic resonance spectroscopy and magnetization transfer imaging, and advanced image processing to...

A mechanism is proposed for manipulating the magnetic state of a helical spin density wave using a current. It is shown that a current through a bulk metal with a helical spin density wave induces a spin transfer torque, which gives rise to a rotation of the order parameter. The use of spin transfer torque to manipulate the magnetization in bulk systems does not suffer from the obstacles seen f...

Quantitative magnetization transfer magnetic resonance imaging provides a means for indirectly detecting changes in the macromolecular content of tissue noninvasively. A potential application is the diagnosis and assessment of treatment response in breast cancer; however, before quantitative magnetization transfer imaging can be reliably used in such settings, the technique's reproducibility in...

Magnetization transfer (MT) techniques provide tissue contrast which depends mainly on the concentration of macromolecules. The magnetization transfer phenomenon is determined by the restricted macromolecular protons and is quantified by the magnetization transfer ratio (MTR). Since many macromolecular structures are implicated in the secretory activity of the pituitary gland, this imaging tech...