Bacteria encounter reactive oxygen species (ROS) as a consequence of the aerobic life or as an oxidative burst of activated neutrophils during infections. In addition, bacteria are exposed to other redox-active compounds, including hypochloric acid (HOCl) and reactive electrophilic species (RES) such as quinones and aldehydes. These reactive species often target the thiol groups of cysteines in...

Vilma Edite Fonseca Heinzen1*, Berenice da Silva Junkes2, Carlos Alberto Kuhnen3 and Rosendo Augusto Yunes1 1Department of Chemistry, Federal University of Santa Catarina, University Campus, Trindade, Florianópolis, Santa Catarina, 2Federal Institute of Education, Science and Technology of Santa Catarina, Mauro Ramos Avenue, No. 950, Center, Florianópolis, SC, 3Department of Physics, Federal Un...

A novel analytical approach involving the addition of an ionic liquid into the mobile phase of the thin-layer chromatography (TLC) system during the optimization of chromatographic separation of peptides was demonstrated. Different behavior of peptides in the TLC sytem was observed after the addition of 1,3-dimethylimidazolium methyl sulfate to the eluent in comparison to the system without the...

Ad Hoc mobile Network (AHNs) may include a plurality of mobile nodes each including a wireless communications device with limited communication resources. Achieving QoS (Quality of Service) in AHNs has been an important research topic in the last years. Hence, we are interested in this paper by the proposition of a global architecture for the offer of a QoS model for AHNs users. Our proposition...

After consumption, pharmaceuticals are excreted as parent compounds and/or metabolites in urine and faeces. Some are not completely removed during wastewater treatments, forcing sewage treatment plants (STPs) to apply alternative technologies to guarantee quality of treated water. To monitor the removal efficiency of STPs, not only unchanged compounds and metabolites have to be taken into accou...

Metabolomics is an emerging field of postgenomic biology concerned with comprehensive analysis of small molecules in biological systems. However, difficulties associated with the identification of detected metabolites currently limit its application. Here we demonstrate that a retention time prediction model can improve metabolite identification on a hydrophilic interaction chromatography (HILI...

O índice semi-empírico topológico, desenvolvido previamente por Heinzen e Yunes, foi aplicado para predizer a retenção cromatográfica de cetonas e aldeídos alifáticos, em fases estacionárias de diferentes polaridades (HP-1, HP-50, DB-210 e Innowax). Foram estabelecidas regressões lineares simples entre os índices de retenção experimentais e os índices semi-empíricos topológicos (RI Exp = a + bI...