EMA (EUROPEAN MEDICINES AGENCY): (A) TRACTO ALIMENTARIO Y METABOLISMO: Fosdenopterina (Nulibry®): deficiencia de cofactor molibdeno. Maralixibat (Livtencity®): prurito colestático.(H) PREPARACIONES HORMONALES SISTÉMICAS: Abaloparatida (Eladynos®): osteoporosis. (J) ANTIINFECCIOSOS SISTÉMICOS: Nirsevimab (Beyfortus®): virus respiratorio sincitial. Vacuna COVID-19 recombinante (VidPrevtyn Beta®):...

High sodium intake is a well-known risk factor for elevated blood pressure and is responsible for a higher incidence of cardiovascular events. Reports have suggested an association of sodium intake with insulin resistance (IR) and type 2 diabetes mellitus in adults. However, evidence on an association between sodium intake assessed on the basis of urinary sodium excretion and IR in adolescents ...

1 Introduction. We consider the class of Noetherian ring, appeared as a result of quantization of algebraic groups and their representations within framework of mathematical physics. One set up the problem of description of prime and primitive spectrum of these rings. This problem has been solved first for algebras of low dimension , then for the case GL q (n), later for general case of regular...

The rich structure of the AΠ−XΣ system of carbon monoxide accounts for many of the spectral features seen in long slit HST -STIS observations of comets 153P/Ikeya-Zhang, C/2001 Q4 (NEAT), and C/2000 WM1 (LINEAR), as well as in the HST -GHRS spectrum of comet C/1996 B2 (Hyakutake). A detailed CO fluorescence model is developed to derive the CO abundances in these comets by simultaneously fitting...

BACKGROUND AND PURPOSE Growth differentiation factor-15 (GDF-15) and soluble (s)ST2 are markers of cardiac and vascular stress. We investigated the associations between circulating concentrations of these biomarkers and incident stroke and subclinical vascular brain injury in a sample from the Framingham Offspring cohort. METHODS We followed 3374 stroke- and dementia-free individuals (mean ag...

The objective of the present study was to investigate the relationship between total and subtypes of bacterial fermented food intake (dairy products, cheese, vegetables and meat) and mortality due to all causes, total cancer and CVD. From the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort, 34 409 Dutch men and women, aged 20-70 years who were free from CVD or ca...

BACKGROUND Fruits and vegetables (F/V) have been examined extensively in nutrition research in relation to colorectal cancer (CRC). However, their protective effect is subject to debate, possibly because of different effects on different subsites of the large bowel. OBJECTIVE To determine whether any association between F/V consumption and risk of CRC differed by subsite of the bowel (proxima...

Objectives: To analyse the relation between serum glucose concentration and hospital outcome across the whole spectrum of acute coronary syndromes. Methods: This was a prospective cohort study of 2127 patients presenting with acute coronary syndromes. The patients were stratified into quartile groups (Q1 to Q4) defined by serum glucose concentrations of 5.8, 7.2, and 10.0 mmol/l. The relation b...

OBJECTIVES To examine the association between leukocyte mitochondrial DNA copy number (mtCN) and different anthropometric indices as well as weight changes; and to compare mtCN and telomere length with respect to their associations with BMI and age. DESIGN Population based cohort study. SETTING Nurses' Health Study, an ongoing prospective cohort study of 121,700 nurses enrolled in 1976; in ...