Pyoderma gangrenosum is strongly associated with inflammatory bowel disease and exhibits pathergy, occurring at sites ofprevious minor trauma. A patient is presented with a 21 year history of extensive ulcerative colitis, who developed pyoderma gangrenosum and arthralgia while receiving high dose corticosteroids for active ulcerative colitis. The arthralgia exhibited pathergy affecting particul...

PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous condition, the etiology of which is poorly understood but is thought to be related to improper neutrophil function and chemotaxis. PG is a clinical diagnosis that requires exclusion of other ulcerative and inflammatory cutaneous disorders. A rare side effect of isotretinoin is the development of ...

Introduction Approximately 45% of stoma patients experience peristomal skin excoriation.1 Common causes include mechanical trauma, infectious dermatitis, and pyoderma gangrenosum. Pyoderma gangrenosum most often is associated with inflammatory bowel disease; presentation may begin with mild excoriation that rapidly develops into painful, pyogenic ulcers within hours or days. Regardless of the c...

PG: pyoderma gangrenosum N eutrophilic disease encompasses a spectrum of conditions characterized by neutrophilic aseptic inflammation in the skin and internal organs. The prototype of this group is pyoderma gangrenosum (PG); however, the existence of transitional and overlap forms is always a consideration when facing patients with autoinflammation. We report on a patient with overlapping neut...

Pyoderma gangrenosum is a great masquerader in wound diagnosis and management. Frequently misdiagnosed as a necrotizing infection, the elusive nature of its etiology and pathogenesis has thwarted the establishment of a standardized management algorithm, leaving immunosuppressant therapies as the mainstay of treatment. The present report describes a 61-year-old woman presenting with temporally d...

Pyoderma gangrenosum is a non-infectious neutro?philic skin disease commonly associated with underlying systemic diseases. Histopathological and laboratory diagnostics are unspecific in the majority of the cases and the diagnosis is made in accordance with the clinical picture. Here, we report the case of a 69-year old man with progredient pyoderma gangrenosum-like ulcerations under treatment w...

Pyoderma gangrenosum is strongly associated with inflammatory bowel disease and exhibits pathergy, occurring at sites ofprevious minor trauma. A patient is presented with a 21 year history of extensive ulcerative colitis, who developed pyoderma gangrenosum and arthralgia while receiving high dose corticosteroids for active ulcerative colitis. The arthralgia exhibited pathergy affecting particul...

Pyoderma gangrenosum is a rare, ulcerative, non-infectious neutrophilic dermatosis, commonly associated with underlying systemic disease. The features of pyoderma gangrenosum are not specific histopathologically and for this reason the diagnosis is based on clinical feature. The systemic administration of corticosteroids is the mainstay of treatment. We present five cases of pyoderma gangrenosu...

Pyoderma gangrenosum is a skin ulcerative necrosis, due to dermal neutrophilic infiltration, through a non-infectious exacerbation of cell -mediated immunity. Being characterized by pathergy, the disease may be triggered by surgery; in this case, it is easily mistaken for a postoperative infection. We report a case of pyoderma gangrenosum after coronary artery bypass surgery. The patient develo...