Production of propionic acid by fermentation of propionibacteria has gained increasing attention in the past few years. However, biomanufacturing of propionic acid cannot compete with the current oxo-petrochemical synthesis process due to its well-established infrastructure, low oil prices and the high downstream purification costs of microbial production. Strain improvement to increase propion...

BACKGROUND Entomological surveys of Simulium vectors are an important component in the criteria used to determine if Onchocerca volvulus transmission has been interrupted and if focal elimination of the parasite has been achieved. However, because infection in the vector population is quite rare in areas where control has succeeded, large numbers of flies need to be examined to certify transmis...

L-asparaginase (ASNase) is an amidohydrolase enzyme widely distributed in nature, e.g., microorganisms, plants and tissues of several animals. Nevertheless, microorganisms are the preferential source ASNase since they usually grow simple substrates culture conditions. However, a high level purity required by pharmaceutical industry, which applied downstream process may account for up to 80% tot...

Economic impacts of agricultural carbon sequestration involve direct costs of sequestration management adoption as well as a variety of indirect costs and benefits. The nature and significance of these impacts are discussed. Spatial and temporal heterogeneity in agriculture is identified as an influential factor. Techniques to estimate the cost of agricultural carbon sequestration are briefly r...

background toxoplasma gondii is an obligatory intracellular protozoan parasite, which infects human beings. since the current antigens used for diagnosis or vaccination are contaminated with non parasitic material in which the parasite is grown, it is tried to produce recombinant antigens to design vaccines against toxoplasmosis, or make diagnostic kits. choosing the type of antigen to produce ...

background: streptokinase is a potent activator of plasminogen to plasmin, the enzyme that can solubilize the fibrin network in blood clots. streptokinase is currently used in clinical medicine as a thrombolytic agent. it is naturally secreted by β-hemolytic streptococci. methods: to reach an efficient method of purification, an immunoaffinity chromatography method was developed that could puri...

The utilization of methanotrophic haloalkaliphilic bacteria for the production ectoine in waste treatment plants has demonstrated a great potential to upgrade traditional use biogas as energy vector and current industrial routes this high added-value chemical (600–1000 €·kg −1 ). However, influence socio-economic aspects such location plant, economy scale market fluctuations on profitability pr...

The conversion of agricultural waste materials such as bark or straw into 2nd generation biofuels constitutes an auspicious way to meet part the future fuel demand in a sustainable way. number possible production routes is diverse, and techno-economic analyses these have been conducted very different ways. route involving gasification, gas purification, subsequent Fischer-Tropsch synthesis enab...

background: botulinum neurotoxin (bont) complexes consist of neurotoxin and neurotoxin-associated proteins. hemagglutinin-33 (ha-33) is a member of bont type a (bont/a) complex. considering the protective role of ha-33 in preservation of bont/a in gastrointestinal harsh conditions and also its adjuvant role, recombinant production of this protein is favorable. thus in this study, ha-33 was expr...

The main purpose of this paper is the techno-economic analysis hydrogen production from biogas via steam reforming in a pilot plant. Process flow modeling based on mass and energy balance used to estimate total equipment purchase operating costs production. plant installation produced 250.67 kg/h 1260 biomethane obtained after purification 4208 m3/h using heat integration process. Despite high ...