We have demonstrated an efficient high-peak-power AlGaInAs eye-safe wavelength disk laser at 1555 nm. The quantum defect and the thermal load are significantly reduced by pumping the quantum well directly. The overall conversion efficiency is enhanced over three times compared with the barrier pumping method. With a pump peak power of 3.7 kW, an output peak power of 0.52 kW is generated at a pu...

Considerable uncertainty surrounds the stoichiometry of coupling of ATP hydrolysis to drug pumping by P-glycoprotein, the multidrug transporter. To estimate relative turnovers for pumping of the drug vinblastine and ATP hydrolysis, we began by measuring the number of P-glycoprotein molecules on the surface of murine NIH3T3 cells expressing the human MDR1 gene. Fluorescence of cells treated with...

When pumping from a single well in a real (heterogeneous) aquifer, the steady state drawdown at the well is proportional to the pumping rate through a value called the equivalent transmissivity, Tea, which, in short, is the value that best suits Thiem's formula. Equivalent transmissivity is not a local value, but some representative value of a certain area surrounding the well. By means of nume...

An analytical solution for the case of transient, pumping-induced drawdown in a nonuniform aquifer is presented. The nonuniform aquifer is conceptualized as a uniform matrix into which a disk of anomalous properties has been placed. The disk can be arbitrarily located with respect tothe pumping well. This solution can be used to develop considerable insight concerning the nature of drawdown i n...

In C. elegans, pharyngeal pumping is regulated by the presence of bacteria. In response to food deprivation, the pumping rate rapidly declines by about 50-60%, but then recovers gradually to baseline levels on food after 24 hr. We used this system to study the role of insulin/IGF-1 signaling (IIS) in the recovery of pharyngeal pumping during starvation. Mutant strains with reduced function in t...

Rhythmic movements are ubiquitous in animal locomotion, feeding, and circulatory systems. In some systems, the muscle itself generates rhythmic contractions. In others, rhythms are generated by the nervous system or by interactions between the nervous system and muscles. In the nematode Caenorhabditis elegans, feeding occurs via rhythmic contractions (pumping) of the pharynx, a neuromuscular fe...

In microfluidic systems, a pump for fluid-driving is often necessary. To keep the size of microfluidic systems small, a pump that is small in size, light-weight and needs no external power source is advantageous. In this work, we present a passive, simple, ultra-low-cost, and easily controlled pumping method based on capillary action of paper that pumps fluid through conventional polymer-based ...

We consider a non-equilibrium generalization of the mixed SYK$_4$+SYK$_2$ model and calculate energy dissipation rate $W(\omega)$ that results due to periodic modulation random quadratic matrix elements with frequency $\omega$. find possesses peak at $\omega$ close polaron splitting $\omega_R$ found recently (PRL 125, 196602), demonstrating physical significance this scale. Next, we study effec...

Austin J Baird: Modeling valveless pumping mechanisms (Under the direction of Laura Miller) Several mechanisms of valveless pumping are studied numerically. The discussion begins with an introduction into the two well-known driving mechanisms of flow in valveless tubes: impedance pumping and peristalsis. Flow generated from peristalsis and impedance pumping is examined using the immersed bounda...