Abstract Background: Insufficient uterine activity or hypotonic uterine contraction is a common reason and the cause of abnormal labor progress that can be corrected with oxytocin. Realizing this fact that undue prolongation of labor may contribute to prenatal morbidity has resulted in using oxytocin infusion in different kinds of ineffective uterine contractions. Materials and methods: In th...

The glucocorticoid hormone cortisol is released in pulses resulting in a complex and dynamic ultradian rhythm of plasma cortisol that underlies the classical circadian rhythm. These oscillating levels are also seen at the level of tissues such as the brain and trigger pulses of gene activation and downstream signalling. Different patterns of glucocorticoid presentation (constant vs pulsatile) r...

In this study, a lumped compartment cardiovascular model is developed to predict pulsatile pressures in the systemic and pulmonary circulation as well as in finger arteries. Essential compartments of the model include arterial and venous pulmonary, left and right ventricles, and arterial and venous systemic compartments. A pulsatile left ventricle is incorporated to be the source of pulse waves...

Westerlund, J. 2000. Pulsatile insulin release from single islets of Langerhans. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 945. 49 pp. Uppsala. ISBN 91-554-4782-1 Insulin release from single islets of Langerhans is pulsatile. The secretory activities of the islets in the pancreas are coordinated resulting in plasma insulin osci...

MR imaging-evident intraosseous channels associated with the presence of a dural arteriovenous fistula have been described in the literature. We describe these channels in relation to a case of dural arteriovenous fistula seen on CT. The presence of this subtle sign should be sought, and the area reviewed in all CT evaluations of patients with pulsatile tinnitus.

Tinnitus is primarily an auditory symptom. Yet not only patients and clinicians, but also current pathophysiological models relate the onset and maintenance of tinnitus to stress. Here physiological and psychological stress reactivity was investigated in 19 patients with subjective chronic tinnitus and 19 comparable healthy controls. All participants underwent five consecutive measurements in o...

161 Abstract: Pulsatile systems are best for the drugs, which follows chronopharmacological behaviour where night time dosing is required, drugs having high first-pass effect and having specific site of absorption in GIT. In this study, colon targeted pulsatile release tablets of atenolol was prepared using press coating technique to treat hypertension in the early hours of the morning. Pulsati...

OBJECTIVE To determine the effect of endotracheal-tube cuff deflation on airflow and F(IO2) during high-frequency percussive ventilation (HFPV), and explore methods of correcting the cuff-deflation-associated decrease in mean airway pressure and F(IO2) at the carina. METHODS Using a mechanical lung model in our respiratory research laboratory, we measured circuit pressure near the connection ...

The use of nonpulsatile flow during extracorporeal circulation remains popular despite theoretical advantages of pulsatile cardiopulmonary bypass (CPB). Pulsatile CPB is considered to be more physiological than nonpulsatile flow as the pulsatile energy ensures the patency of the vascular bed and mechanical motion of tissue fluid around the cell membrane, improves microcirculation and enhances d...