BACKGROUND AND OBJECTIVE Dental pulp repair is a common process triggered by microbial and mechanical challenges. Matricellular modulators, such as periostin, are key for extracellular matrix stability and tissue healing. In the scope of the dental pulp, periostin expression has been reported during development and active dentinogenesis. However, the specific dental pulp cell population capable...

background: accurate diagnosis is key to success. diagnosing the pulpal status in varied clinical situations poses a challenge to the clinician. electric pulp test (ept) is one of the valuable attempts in evaluating the sensibility of pulp tissue. the aim of this study was to find out and compare the threshold levels and optimal electrode placement site for ept in fluorosed and nonfluorosed ant...

The understanding of the caries process and its effect on the pulp is presented in the context that caries does develop in various rates of progression. Early in the caries process, the pulp reflects changes within lesion activity. Thus, the early pulp response is reversible. Later, the rate of caries progression is reflected by the quality of the tertiary dentin. Slowly progressing lesions cre...

Sixty-three vital permanent incisors with complicated crown fractures were treated by partial pulpotomy and assessed clinically and radiographically for healing. Healing of the pulp was considered to have taken place when the following criteria were fulfilled: absence of clinical symptoms, radiographic evidence of dentin bridge formation, no intrapulpal or periapical pathosis, continued root de...

AIM To evaluate the clinical and radiological response of primary molars to direct pulp capping with calcium sulfate hemihydrate. MATERIALS AND METHODS Forty primary molar teeth in 40 healthy children aged 5-9 years were treated by direct pulp capping. Teeth were randomly assigned to two groups (n=20) according to material used for capping, as follows: Group 1: calcium hydroxide cement (Dycal...

Caries, pulpitis, and apical periodontitis increase health care costs and attendant loss of economic productivity. They ultimately result in premature tooth loss and therefore diminishing the quality of life. Advances in vital pulp therapy with pulp stem/progenitor cells might give impetus to regenerate dentin-pulp complex without the removal of the whole pulp. Tissue engineering is the science...

INTRODUCTION Pulpal reactions after acute dental injury have been puzzling for many clinicians. The management of dental trauma and an understanding of clinical and treatment factors in outcomes arose from multivariate statistical analyses of archive material from Copenhagen. METHODS The aim of this article was to review the works of this period with respect to pulpal reaction after acute mec...

INTRODUCTION The aim of this randomized clinical trial was to compare the histologic pulp tissue response to one-step direct pulp capping (DPC) and miniature pulpotomy (MP) with mineral trioxide aggregate (MTA) after application of dexamethasone in healthy human premolars. METHODS AND MATERIALS Forty intact premolars from 10 orthodontic patients, were randomly chosen for DPC (n=20) or MP (n=2...

b o m o B e c t e bstract his randomized crossover double-blind trial compared he efficacy of buccal infiltration with 4% articaine and % lidocaine (both with 1:100,000 epinephrine) in ecuring mandibular first molar pulp anesthesia. Injecions were given at least 1 week apart in 31 healthy dult volunteers. Electronic pulp testing was underaken at baseline and at 2 minute intervals until 30 inute...

Pulpitis is a typical inflammatory disease of dental pulp, characterized by the local accumulation of inflammatory mediators, including cytokines and chemokines. In addition to serving as intercellular messengers mediating the inflammatory response, cytokines and chemokines induce the expression and stimulate the activity of molecular and cellular agents which participate actively in destructiv...