Polyphosphate (polyP), a polymer of orthophosphate moieties released from the dense granules of activated platelets, is a procoagulant agent. Inositol pyrophosphates, another group of phosphate-rich molecules, consist of mono- and diphosphates substituted on an inositol ring. Diphosphoinositol pentakisphosphate (IP7), the most abundant inositol pyrophosphate, is synthesized on phosphorylation o...

Polypectomy is the standard therapy for gastrointestinal pedunculated polyps [1]. However, achieving effective countertraction to snare the stalk of the polyp located in the direction of gravity can sometimes be difficult [2]. Herein, we present a case of a large gastric polyp located on the greater curvature of the gastric body that was resected using the “water immersion” technique in order t...

A fibrovascular polyp is a rare benign disease of the upper digestive tract and is usually located in the esophagus. To our knowledge, this is the first case of gastric fibrovascular polyp presenting with melena reported in the English literature. The polyp was well visualized on endoscopy and removed with laparoscopic wedge resection. Histology confirmed fibrovascular polyp of the stomach.

Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select those ima...

Sphenochoanal polyp is a rare form of choanal polyp which originates from the sphenoid sinus and extends to posterior choanae via sphenoethmoidal recess. Its occurrence is extremely rare. They can be easily mistaken for antrochoanal polyp. Symptomatically, it is similar to antrochoanal polyp. So, adequate preoperative evaluation with diagnostic nasal endoscopy and computed tomography or magneti...

Fibroepithelial pharyngeal polyps are rare. We herein report a case of a 56-year-old Asian woman who presented with voice hoarseness and throat discomfort for several years because of a giant pharyngeal polyp. We resected the polyp under general anesthesia. It originated in the left hypopharyngeal wall. Postoperative recovery was uneventful. Her sore throat was diminished within 1 week after th...

A gastric inverted hyperplastic polyp is a rare type of gastric polyp and is characterized by downward growth of a variety of mucosal components into the submucosa. The polyp consists of columnar cells resembling foveolar epithelium and pyloric gland epithelium and can coexist with gastritis cystica profunda. Frequently, adenocarcinoma can coexist, but the relation is not clear. A 77-year-old m...

Polyphosphate (polyP) consists of tens to hundreds of phosphates, linked by ATP-like high-energy bonds. Although polyP is present in mammalian mitochondria, its physiological roles there are obscure. Here, we examine the involvement of polyP in mitochondrial energy metabolism and ion transport. We constructed a vector to express a mitochondrially targeted polyphosphatase, along with a GFP fluor...

polymers, ϳ 70 mer to 250 mer, are more effective in abrogating tissue factor pathway inhibitor–anticoagulant activity. In the case of fibrin clot stabilization, polyP polymers shorter than 100 mers had no influence on fibrin clot turbidity whereas Ն 250 mer support maximal turbidity increase. Interestingly, very short phosphates, particularly PPi, effectively block the polyP-mediated enhanceme...

Introduction Parotid gland squamous cell carcinoma is an uncommon aggressive neoplasm with poor prognosis. Aural polyps are usually the presenting features of chronic suppurative otitis media, tuberculous otitis media, and adenoma or carcinoma. The malignant aural polyp is very rare. Parotid gland carcinoma masquerading as an aural polyp has rarely been described in the literature. ...