In seven postoperative patients with normal preoperative pulmonary function tests, we evaluated the oxygen cost of breathing (VO2resp) during continuous positive pressure ventilation (CPAP) and during a 15 cm H2O inspiratory pressure support ventilation (IPSV). For both periods, VO2 resp was estimated as the difference between total oxygen uptake of the period (VO2tot), measured by a mass-spect...

BACKGROUND General anesthesia usually requires mechanical ventilation, which is traditionally accomplished with constant tidal volumes in volume- or pressure-controlled modes. Experimental studies suggest that the use of variable tidal volumes (variable ventilation) recruits lung tissue, improves pulmonary function and reduces systemic inflammatory response. However, it is currently not known w...

The effects of ventilation with He-O2 during decompression sickness (DCS) and venous air embolism were studied. Fifteen anesthetized dogs were mechanically ventilated and subjected to repeated air dives until pulmonary artery pressure at least doubled within 10 min postdive. At 30 min postdive, ventilation was either continued with air (controls, n = 7) or changed to He-O2 (n = 8) for an additi...

Assisted modes of mechanical ventilation, including synchronous intermittent mandatory ventilation, pressure support ventilation (PSV), continuous mandatory ventilation, neurally adjusted ventilatory assist, and volume guarantee ventilation, are widely used in neonates, infants, and small children to achieve improved short-term and long-term outcomes.1-3 Specifically, evidence is accumulating t...

BACKGROUND Intermittent positive pressure ventilation applied through a nasal mask has been shown to be useful in the treatment of chronic respiratory insufficiency. Pressure support ventilation is an assisted mode of ventilation which is being increasingly used. Invasive ventilation with intermittent positive pressure, with or without positive end expiratory pressure (PEEP), has been found to ...

Introduction Impaired right ventricle (RV) function is associated with worse outcome in ARDS. Pulmonary artery pressure waveform analysis provides information about phenomena that affect RV performance. In particular, pulmonary vascular wave reflection (WR) is directly related with RV stress. We hypothesised that open lung ventilation (OLV), compared with conventional ARDS-net ventilation (CV),...

Changes in the mean pulmonary wedge pressure were measured during temporary disconnection from a ventilator in 29 patients to assess the effects of therapy with controlled-volume ventilation on determinations of pulmonary wedge pressure. In 16 observations performed during therapy with intermittent positive-pressure ventilation, the mean value for the pulmonary wedge pressure was the same (10.3...

Background: Domiciliary non-invasive ventilation may be used in palliative care of patients with chronic obstructive pulmonary disease, although there is uncertainty regarding effect on quality of life. Aim: Explore experiences of domiciliary non-invasive ventilation in chronic obstructive pulmonary disease, to understand decisionmaking processes and improve future palliative care. Design: Qual...