This prospective study investigated the value of serum total prostate specific antigen (tPSA)-based parameters in the diagnosis of prostate cancer (PCa). Serum tPSA, free to tPSA ratio (f/tPSA), PSA density (PSAD), and PSA transition zone (PSAT) were evaluated in 110 patients with histologically confirmed benign prostate hyperplasia (BPH) and 98 patients with PCa. Once the serum tPSA was elevat...

background: we aimed to value the usefulness of free to total prostate-specific antigen and prostate-specific antigen (psa) density for prostate cancer in the patients with psa levels of 4.0 ng/ml or less. methods: a total of 343 subjects with psa levels of 4.0 ng/ml or less were biopsied. all patients were divided into four groups according to the psa levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, ...

background: prostate cancer is the most common malignancy among the male population in the united states and the 3rd most common non-skin cancer among men in iran. its prevalence has shown a rising trend in recent decades. the aim of this study was to report the epidemiological features of prostate cancer in patients referred for prostate biopsy in the south of iran and to evaluate the accuracy...

Objective: To determine the diagnostic accuracy of PSA density in Prostate Cancer, Benign Prostatic Hyperplasia (BPH) and Prostatitis, taking biopsy as gold standard.
 Study Design: Cross-sectional study.
 Place Duration Study: Chemical Pathology Endocrinology Department, Armed Forces Institute (AFIP) collaboration with Histopathology department, AFIP, Urology (AFIU) Radiology (AFIRI)...

The cyanobacterial PSI complex is a membrane-bound, photooxidoreductase that catalyzes the light-driven transport of electrons from reduced plastocyanin (or Cyt cSs3) to oxidized, soluble Fd or flavodoxin (for a review, see Golbeck and Bryant, 1991). The complex probably comprises single copies of 11 or 12 different polypeptides, about 100 Chl a molecules, 10 to 15 p-carotene molecules, 2 molec...

Introduction: Prostate cancer is among the most common malignancies in men which can be well-managed if early diagnosed. Nevertheless, to date, no accurate index has been detected order differentiate prostate from other benign conditions practically except biopsies that an invasive procedure. Objectives: The current study aimed assess values of urinary antigen 3 (PCA3) diagnosis. Patients and M...

Table S1. Characteristics according to D’Amico risk classification in PCa patients treated by radical prostatectomy. Table S2. Univariate analysis to predict intermediate-risk subgroups having a comparable risk of biochemical recurrence to that in the high-risk group. Table S3. OR of adverse pathological outcome according to PSAD levels in patients with the intermediate-risk group. Table S4. Mu...

For lung cancer, the Peto et al. method involves approximating national non-smoker death rates by the death rates of a reference population of non-smokers. Lung cancer attributable mortality in a given country is thus calculated as the di erence between total national death rates and the respective death rates in the reference population. For other smoking-related diseases, we calculate the pro...

The necessity of routine prostate biopsy prior to transurethral resection of the prostate (TURP) in elderly comorbid patients with a high prostate specific antigen (PSA) level remains controversial. We assessed the role of TURP in prostate cancer diagnosis in these individuals. A total of 197 patients underwent TURP in conjunction with prostatic needle biopsy. Pathologic reviews of specimens of...

INTRODUCTION The role of fungal infection as a causative factor for prostatitis is currently underestimated. The aim of our work was to evaluate the response to an antifungal regimen in the setting of patients presenting with symptoms of chronic pelvic pain syndrome that have been refractory to treatment with antibiotics and alpha-blockers. MATERIAL AND METHODS We included 1,000 consecutive p...