نتایج جستجو برای: protoporphyin ix

تعداد نتایج: 18973  

Journal: :Blood 1985
W Kisiel K J Smith B A McMullen

Coagulation factor IX is a vitamin K-dependent glycoprotein that circulates in blood as a precursor of a serine protease. Incubation of human factor IX with human alpha-thrombin resulted in a time and enzyme concentration-dependent cleavage of factor IX yielding a molecule composed of a heavy chain (mol wt 50,000) and a doublet light chain (mol wt 10,000). The proteolysis of factor IX by thromb...

Journal: :Physical chemistry chemical physics : PCCP 2015
Seema Singh Anirban Chakraborty Vandana Singh Aniruddha Molla Sahid Hussain Manoj K Singh Prolay Das

Photodynamic therapy (PDT) involves generation of reactive oxygen species (ROS) by the irradiation of a photosensitizer. Controlled and targeted release of ROS by a photosensitizer is crucial in PDT. For achieving controlled generation of ROS, a ZnSe/ZnS quantum dot (QD) donor and protoporphyrin IX (Pp IX) acceptor based fluorescence resonance energy transfer (FRET) probe is reported here. The ...

Journal: :The Biochemical journal 1997
M Perälä M Savontaus M Metsäranta E Vuorio

Several techniques were used to study the co-ordination of mRNA levels for five constituent chains of cartilage collagen fibrils during mouse development. Short cDNA clones were first constructed for mouse and human alpha3(IX) and for mouse proalpha1(XI) collagen mRNA species. Northern analysis of developing mouse embryos revealed that the mRNA species for alpha1, alpha2 and alpha3 chains of ty...

2014
Janina Moeker Brian P. Mahon Laurent F. Bornaghi Daniela Vullo Claudiu T. Supuran Robert McKenna Sally-Ann Poulsen

Carbonic anhydrase IX (CA IX) is an extracellular transmembrane homodimeric zinc metalloenzyme that has been validated as a prognostic marker and therapeutic target for several types of aggressive cancers. CA IX shares a close homology with other CA isoforms, making the design of CA IX isoform selective inhibitors challenging. In this paper, we describe the development of a new class of CA IX i...

رنجبر امیدی , دکتر بهاران , میرزایی, دکتر منصوره , کرمانشاه , دکتر حمید , یاسینی, دکتر اسماعیل ,

  بررسی اثر سیکل مکانیکی بر ریزنشت ترمیمهای Cl V کامپوزیت و گلاس آینومر   و ارزیابی SEM ‌آن     دکتر اسماعیل یاسینی 1 - دکتر حمید کرمانشاه 2 - دکتر منصوره میرزایی2 - دکتر بهاران رنجبر امیدی 3   1- عضو مرکز تحقیقات دندانپزشکی و استاد گروه آموزشی دندانپزشکی ترمیمی و زیبایی دانشکده دندانپزشکی دانشگاه علوم پزشکی تهران   2- استادیار گروه آموزشی دندانپزشکی ترمیمی و زیبایی دانشکده دندانپزشکی دانشگاه ع...

2017
Katarina Kalavska Zuzana Cierna Michal Chovanec Martina Takacova Daniela Svetlovska Viera Miskovska Jana Obertova Patrik Palacka Jan Rajec Zuzana Sycova-Mila Katarina Machalekova Karol Kajo Stanislav Spanik Jozef Mardiak Pavel Babal Silvia Pastorekova Michal Mego

Testicular germ cell tumors (TGCTs) represent a highly curable malignancy, however a small proportion of patients fails to be cured with cisplatin-based chemotherapy. Carbonic anhydrase IX (CA IX) is upregulated by hypoxia in several cancer types and correlates with a poor prognosis. The present translational study evaluated expression and prognostic value of CA IX in TGCTs. Surgical specimens ...

Journal: :dental research journal 0
sayed mostafa mousavinasab ian meyers

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: to measure the amounts of fluoride released from fluoride-containing materials, four glass ionomer cements (fuji ix, fuji vii, fuji ix extra and fuji ii lc), a compomer (dyract extra) and a giomer (beautifil) were used in this study . methods: twenty cylindrical specimens were prepared from each material. the a...

Journal: :Plant physiology 1989
D A Witkowski B P Halling

The effect of acifluorfen-methyl on tetrapyrrole synthesis in greening chloroplasts of Cucumis sativus was examined. Formation of Mg-proto-porphyrin IX from delta-aminolevulinate was reduced 98% by 10 micromolar acifluorfen-methyl. Conversion of protoporphyrin IX to Mg-protoporphyrin IX was unaffected, but protoporphyrin IX synthesis from delta-aminolevulinate was blocked, indicating a site of ...

2016
Katarina Kalavska Michal Chovanec Miriam Zatovicova Martina Takacova Paulina Gronesova Daniela Svetlovska Magdalena Baratova Vera Miskovska Jana Obertova Patrik Palacka Jan Rajec Zuzana Sycova-Mila Zuzana Cierna Karol Kajo Stanislav Spanik Pavel Babal Jozef Mardiak Silvia Pastorekova Michal Mego

Despite the fact that testicular germ cell tumors (TGCTs) are one of the most chemosensitive solid tumors, a small proportion of patients fail to be cured following cisplatin-based first line chemotherapy. Upregulation of carbonic anhydrase IX (CA IX) in various solid tumors is associated with poor outcome. The current prospective study investigated the prognostic value of serum CA IX level in ...

2001
Louis Ignarro Bryan Ballot Keith Wood

Alterations of the chemical structure of protoporphyrin IX markedly altered the activation of soluble guanylate cyclase purified from bovine lung. Hydrophobic side chains at positions 2 and 4 and vicinal propionic acid residues at positions 6 and 7 of the porphyrin ring (protoporphyrin IX, mesoporphyrin IX) were essential for maximal enzyme activation (K. = 7-8 nM; V, = 6-8 Kmol of cGMP/min/mg)...

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