نتایج جستجو برای: protein binding

تعداد نتایج: 1446869  

H.E. Rushdi H.I. Shafey, K.F. Mahrous M. Abdel Mordy M.S. Hassanane

The genetic polymorphism of some genes related to meat production in three Egyptian sheep breeds (Barki, Rahmani and Osseimi) was studied. The candidate genes were: Calpastatin, Myostatin, Diacylglycerol-acyltransferase1, Insulin-like growth factor binding protein-3 and Booroola fecundity gene. The technique applied was the restriction fragment length polymorphism for the polymerase chain react...

Journal: :cell journal 0
chiranjib chakraborty bidyut mallick ashish ranjan sharma garima sharma supriya jagga c george priya doss

objective: druggability of a target protein depends on the interacting micro-environment between the target protein and drugs. therefore, a precise knowledge of the interacting micro-environment between the target protein and drugs is requisite for drug discovery process. to understand such micro-environment, we performed in silico interaction analysis between a human target protein, dipeptidyl...

Journal: :journal of sciences, islamic republic of iran 2013
a. divsalar s. khodabakhshian a.a. saboury h. mansuri-torshizi m. evini

human serum albumin (hsa) is an abundant, multifunctional and nonglycosylated negatively charged plasma protein. hsa ascribed ligand-binding and transport properties, antioxidant functions and enzymatic activities. in the present study, the interaction and side effects of a new designed anti-cancer compound (1,10-phenanthroline butyl dithiocarbamato palladium(ii) nitrate) on hsa have been inves...

Journal: :iranian biomedical journal 0
مصیب رستمیان mosayeb rostamian سید جعفر موسوی seyed jafar mousavy فیروز ابراهیمی firouz ebrahimi سید ابوالقاسم قدمی seyyed abolghasem ghadami نادر شیبانی nader sheibani محمد ابراهیم مینایی mohammad ebrahim minaei محمد علی عارف پور ترابی

background: recently, botulinum neurotoxin (bont)-derived recombinant proteins have been suggested as potential botulism vaccines. here, with concentrating on bont type e (bont/e), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of bont serotypes a, b and e binding subdomains, and a monovalent recombinant protein, which contains...

Journal: :iranian biomedical journal 0
نونا ابوالحسنی nona abolhassani مجید صادقی زاده majid sadeghi zadeh غلامرضا جوادی golamreza javadi مظفر صادقی زاده mozafar sadeghi zadeh هاله رفعتی haleh rafati

background: recent research on several dna fragments covering open reading frames (orf) 1-37 shows a new genetic marker in orf 6 which is specific for differentiating wild-type varicella-zoster virus (vzv) strains from oka varicella vaccine strain. on the other hand, herpes simplex virus (hsv) genome analysis by restriction enzymes is used to differentiate types one and two of the virus and eve...

Journal: :physical chemistry research 0
samira gholami university of isfahan abdol-khalegh bordbar university of isfahan

because of participation in many aspects of human life, and due to oxidation-sensitive characteristics of dopamine (da) and arachidonoyl dopamine (aa-da), the necessity of biocompatible carrier to keep them against oxidation is of importance. in this work, we explored the putative binding sites of da and aa-da to -lactoglobulin (blg) as potent carrier. docking results identified the binding si...

F. Tohidinejad M.R. Mohammadabadi,

The aim of the present study was todeterminecharacteristics of Rheb gene and protein in Raini Cashmere goat. Comparative analyses of the nucleotide sequences were performed. Open reading frames (ORFs), theoretical molecular weights of deduced polypeptides, the protein isoelectric point, protein characteristics and three-dimensional structures was predicted using online standard softwares. The f...

Journal: :iranian journal of microbiology 0
sanaz dehbashi department of pathobiology, school of public health , tehran university of medical sciences, tehran, iran. mohamadreza pourmand urology research center, tehran university of medical sciences, tehran, iran. rahil mashhadi urology research center, tehran university of medical sciences, tehran, iran.

background and objectives: streptococcus agalactiae is the leading cause of bacterial sepsis and meningitis in newborns and results in pneumonia and bacteremia in adults. a number of s. agalactiae components are involved in colonization of target cells. destruction of peptidoglycan and division of covalently linked daughter cells is mediated by autolysins. in this study, autolytic activity and ...

Journal: :avicenna journal of medical biotechnology 0

background: tumour suppressor genes such as tp53, brca1 and rad51 are involved in dna repair and their malfunctions result in genomic instability and cancer. wild type (wt) tp53 binds to brca1and rad51 in vivo and in vitro. however, mutated tp53 in tumours can interfere with wt tp53 function. we studied how mutation of tp53 in mda-mb-468 cell line could affect its binding capacity and interfere...

Firouz Ebrahimi, Mohammad Ali Arefpour Torabi, Mohammad Ebrahim Minaei, Mosayeb Rostamian, Nader Sheibani, Seyed Jafar Mousavy, Seyyed Abolghasem Ghadami,

Background: Recently, botulinum neurotoxin (BoNT)-derived recombinant proteins have been suggested as potential botulism vaccines. Here, with concentrating on BoNT type E (BoNT/E), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of BoNT serotypes A, B and E binding subdomains, and a monovalent recombinant protein, which contains...

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