Parameter estimation of large bio-pathway models is an important and difficult problem. To reduce the prohibitive computational cost, one approach is to decompose a large model into components and estimate their parameters separately. However, the decomposed components often share common parts that may have conflicting parameter estimates, as they are computed independently within each componen...

Parameter estimation of large bio-pathway models is an important and difficult problem. To reduce the prohibitive computational cost, one approach is to decompose a large model into components and estimate their parameters separately. However, the decomposed components often share common parts that may have conflicting parameter estimates, as they are computed independently within each componen...

The idea of a variable dark energy has been entertained many times in the literature and from many different points of view. Quintessence is just a popular way to implement this idea in recent times, but so far with little success. Another possibility is to think of the cosmological term, Λ, as a “running quantity” much in the same way as the electromagnetic coupling constant. However, the fact...

We present a bi-metric theory of gravity containing a length scale of galactic size. For distances less than this scale the theory satisfies the standard tests of General Relativity. For distances greater than this scale the theory yields an effective gravitational constant much larger than the locally observed value of Newton's constant. The transition from one regime to the other through the ...

Objects Abstract Objects Abstract Objects Fig. 3: LLNL Compositional Dataflow Framework. By mapping the Sage IR (e.g. variable or expression) to its corresponding Abstract Objects, client analyses can query the relevant value for any expression. For example, constant propagation analysis can output a map of expressions and their corresponding constant values. A successor analysis can query the ...

In this updated and expanded version of our delayed Comment we show that the np backward cross section, as presented by the Uppsala group[1], is seriously flawed (more than 25 sd.). The main reason is the incorrect normalization of the data. We also show that their extrapolation method, used to determine the charged πNN coupling constant, is a factor of about 10 less accurate than claimed by Er...

In this paper, a photonic crystal waveguide with point defects and lattice constant perturbations of +5%, -5% are being investigated. Firstly waveguide structures with constant and specific parameters are being studied and photonic band gap diagrams for TE/TM modes are depicted; then pulse propagation in the frequencies available in the band gap are shown. After that, effects of parameters like...

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