BACKGROUND Knee osteoarthritis (KOA) is a common disabling disease. Limited studies have demonstrated that prolotherapy with dextrose or with prolozone can be helpful in the treatment of patients with KOA. OBJECTIVES In the current study, we compared the results between these two treatment methods. PATIENTS AND METHODS In the current randomized clinical trial, 80 patients with mild to moder...

PROLOTHERAPY IS the treatment of relaxed ligaments by the injection of sclerosing agents into the ligaments and tendons. This sets up a proliferative reaction which follows the laws of inflammation the end result of which is the formation of fibrous connective tissue. The application of Prolotherapy to treatment of low back pain and sciatica is derived from the work of Leriche and Steindler. Le...

conclusions significant improvement was noted at womac scale (pain level; 5 points, stiffness level; 2 points, physical function loss; 15 points, and total womac 22 points). osteoarthritis level of the patient was improved to grade i at radiological evaluation after a year. our case is the report that presents radiological evidence in addition to clinical findings of improvement of osteoarthrit...

Abstract Background Meralgia paresthetica is an entrapment neuropathy. Neuropathic pain was reported to be improved by using neural prolotherapy. Aim of the research assess and evaluate short-term efficacy prolotherapy on relieving pain, paresthesia improving function quality life patients with meralgia paresthetica. The study included 19 lower limbs idiopathic obtained from 15 patients. Subcut...

To the Editor: The idea of inducing inflammation of a joint and adjacent structures to allow for the proliferation of scar tissue in an effort to stabilize a joint is not a new one. In the fifth century BC, Hippocrates supposedly treated separated shoulders by cauterizing areas of the shoulder to promote axillary scarring. Sclerotherapy, the injection of areas around the enthesis with an inflam...

Prolotherapy reinitiates the inflammatory process thereby augmenting the natural healing process of the body by stimulating fibroblastic activity. It is a promising approach in the management of TMDs, especially in refractory cases where conservative management has failed and in patients where surgical management is not possible. The osmotic agent used is dextrose. It produces a hypertonic extr...