Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central nervous system, ranging from the regulation of gene transcription, cellular signaling, modulation of synaptic structure, and transmission and glial function to behavior. Their actions are mediated by glucocorticoid and mineralocorticoid receptors which are nuclear receptors/transcription factors. While GCs pr...

in this study, the effect of drought stress on morphological and physiological characteristics of wheatgrass and tall fescue was investigated in a factorial-split plot in time arrangement based on a completely randomized design with three replications. after turf establishment, half pots were exposed to drought stress and the half other were completely irrigated. based on the results tall fescu...

BACKGROUND Psychosocial stress is becoming a major contributor to increased mental ill-health and sick leave in many countries. Valid markers of chronic stress would be valuable for diagnostic and prognostic purposes. A recent study suggested monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) as markers of chronic stress. We aimed...

Though horses synthesize ascorbic acid in their liver in amounts that meet their needs under normal circumstances, prolonged stress results in low plasma concentrations due to enhanced utilization and renal excretion and can reduce immune function. It was hypothesized that plasma ascorbic acid could be maintained in weanling horses by oral supplementation following prolonged transportation. Wea...

Adrenomedullin was originally isolated from pheochromocytoma cells and reduces insulin resistance by decreasing oxidative stress. White matter lesions induced by aging and hyperglycemia play a crucial role in cognitive impairment in poststroke patients. Here, we examine whether adrenomedullin deficiency and aging exacerbate ischemic white matter injury after prolonged cerebral hypoperfusion. Ad...

Baccalaureate students enrolled in 6 accelerated programs reported their stress level, sources of stress, and coping strategies. They differentiated helpful from unhelpful coping strategies. Findings indicate that accelerated nursing students experienced high stress levels over prolonged periods that exceeded stress levels in prior life events. Implications for nurse educators in accelerated nu...

Increased oxidative stress during prolonged endurance exercise may end up with muscle damage, fatigue and decreased physical performance. We have recently shown that acute exercise at moderate intensity induced lipid peroxidation, protein oxidation and oxygen radical absorbance capacity (ORAC) in trained trotters. The aim of this study was to measure the changes in oxidative stress and antioxid...

pegylated polypropyleneimine (ppi) dendritic scaffold was used for the delivery of an anti-leukemic drug, imatinib. the current study evolves and emerges the use pegylated ppi dendritic scaffold for the delivery of this drug. in this imatinib was synthesized and loaded with pegylated ppi dendritic scaffold. parameters such as ft-ir, nmr, sem, drug release, dsc and hemolytictoxicity are required...

Abstract The article presents data on the deformation of elastic aftereffect concretes various compositions, at different stress levels prolonged loading, effect loading strength and diagram concrete work. Development relative creep deformations steamed concrete. development aftereffects natural hardening B series under stress. Data studied concretes. e_p(t) including after unloading samples.